TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Binding affinity of the compound against human thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Binding affinity of the compound against thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Binding affinity of the compound against thymidylate synthaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Binding affinity of the compound against Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Antibacterial activity against Streptococcus faecalis assessed as growth inhibitionMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+4nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+4nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 2.03E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.73E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.66E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.66E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.26E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.60E+4nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair