Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]raclopride from human D2 dopamine receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:The ability of test compounds to displace 3H-raclopride at the D2s receptor can be determined on membranes from D2s-transfected CHO cells (Bmax 13 pm...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]raclopride from human D2 dopamine receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:The ability of test compounds to displace 3H-raclopride at the D2s receptor can be determined on membranes from D2s-transfected CHO cells (Bmax 13 pm...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:The ability of test compounds to displace 3H-raclopride at the D2s receptor can be determined on membranes from D2s-transfected CHO cells (Bmax 13 pm...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]flunitrazepam from human alpha2beta3gamma2 GABA receptor in Sf9 membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of human recombinant NET expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human recombinant NET expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human recombinant NET expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of NET in rat synaptosomal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human recombinant NET expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Inhibition of human recombinant NET expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Displacement of [3H]flunitrazepam from human alpha2beta3gamma2 GABA receptor in Sf9 membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8.30nMAssay Description:Displacement of [3H]flunitrazepam from human alpha2beta3gamma2 GABA receptor in Sf9 membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 8.40nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:The ability of test compounds to displace 3H-raclopride at the D2s receptor can be determined on membranes from D2s-transfected CHO cells (Bmax 13 pm...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human recombinant NET expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human recombinant NET expressed in HEK cellsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]flunitrazepam from human alpha5beta3gamma2 GABA receptor in Sf9 membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]flunitrazepam from human alpha5beta3gamma2 GABA receptor in Sf9 membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human recombinant NET expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]raclopride from human D2 dopamine receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of human recombinant NET expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair