Compile Data Set for Download or QSAR
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Found 21 with Last Name = 'west' and Initial = 'fg'
TargetSolute carrier family 2, facilitated glucose transporter member 5(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50300883(6-Deoxy-6-fluoro-D-fructose | CHEMBL568641)
Affinity DataKi:  1.54E+5nMAssay Description:Inhibition of GLUT5-mediated [14C]D-fructose uptake in human MCF7 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 2, facilitated glucose transporter member 5(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50300883(6-Deoxy-6-fluoro-D-fructose | CHEMBL568641)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of GLUT5-mediated [14C]D-fructose uptake in human MDA-MB-231 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 2, facilitated glucose transporter member 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50300883(6-Deoxy-6-fluoro-D-fructose | CHEMBL568641)
Affinity DataKi:  9.16E+5nMAssay Description:Inhibition of GLUT2-mediated [14C]D-glucose uptake in human MCF7 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 2, facilitated glucose transporter member 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50300883(6-Deoxy-6-fluoro-D-fructose | CHEMBL568641)
Affinity DataKi:  6.21E+6nMAssay Description:Inhibition of GLUT2-mediated [14C]D-glucose uptake in human MDA-MB-231 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50504115(CHEMBL4470176)
Affinity DataIC50:  330nMAssay Description:Inhibition of human His6-tagged ERCC1-XPF endonuclease activity expressed in Escherichia coli BL21 (DE3) using [6-FAM-5'-CAGCGCTCGG(20T)CCGAGCGCTG-3'...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50555906(CHEMBL4759590)
Affinity DataIC50:  490nMAssay Description:Inhibition of human His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells using 6-FAM-5'CAGCGCTCGG(20T)CCGAGCGCTG-3'-dabcyl measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50504115(CHEMBL4470176)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50504115(CHEMBL4470176)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50504115(CHEMBL4470176)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50504115(CHEMBL4470176)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells using 6-FAM-5'CAGCGCTCGG(20T)CCGAGCGCTG-3'-dabcyl measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human His6-tagged ERCC1-XPF endonuclease activity expressed in Escherichia coli BL21 (DE3) using [6-FAM-5'-CAGCGCTCGG(20T)CCGAGCGCTG-3'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50504115(CHEMBL4470176)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50555906(CHEMBL4759590)
Affinity DataKd:  85nMAssay Description:Binding affinity to His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells by steady-state fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataKd:  140nMAssay Description:Binding affinity to His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells by steady-state fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-1/repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50504115(CHEMBL4470176)
Affinity DataKd:  100nMAssay Description:Binding affinity to human His6-tagged ERCC1-XPF expressed in Escherichia coli BL21 (DE3) by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed