Compile Data Set for Download or QSAR
maximum 50k data
Found 370 with Last Name = 'wheeldon' and Initial = 'a'
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277511(3-[(3aR,4R,5S,7aS)-5-{(1R)-1-[3,5-Bis(trifluoromet...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to human NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277511(3-[(3aR,4R,5S,7aS)-5-{(1R)-1-[3,5-Bis(trifluoromet...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to human NK3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180545(2-(3,5-bis(trifluoromethyl)benzyloxy)-6-(2-methyl-...)
Affinity DataKi:  100nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178273(CHEMBL202775 | N-((2-(2-cyclopropoxy-5-(trifluorom...)
Affinity DataKi:  190nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178267(CHEMBL201362 | N-(2-methoxy-5-(trifluoromethoxy)be...)
Affinity DataKi:  240nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178271((2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino...)
Affinity DataKi:  270nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180546(2-(3,5-bis(trifluoromethyl)benzyloxy)-1-phenyl-8-a...)
Affinity DataKi:  300nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178270(CHEMBL382803 | N-(2-cyclopropoxy-5-(trifluorometho...)
Affinity DataKi:  360nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178269(CHEMBL382848 | N-((2-(2-cyclopropoxy-5-(trifluorom...)
Affinity DataKi:  420nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180553(2-(3,5-bis(trifluoromethyl)benzyloxy)-6-(1-methyl-...)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180554(2-(3,5-bis(trifluoromethyl)benzyloxy)-1-phenyl-6-(...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178274(CHEMBL202141 | N-(2-chloro-5-(trifluoromethoxy)ben...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185068((7S,8R)-7-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067935((2-Methoxy-5-trifluoromethoxy-benzyl)-((2S,3S)-2-p...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180547(2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185073((6S,7S)-7-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180548(2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1...)
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185062((3R,5S,6S)-5-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180550(2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6...)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178266(2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino)...)
Affinity DataKi:  4.80E+3nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180555(2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178268(2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino)...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185066((3R,5S,6S)-5-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataKi:  5.40E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178276(5-(2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylami...)
Affinity DataKi:  5.80E+3nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178272(CHEMBL201192 | N-(2-cyclopropoxy-5-(trifluorometho...)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178265(2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino)...)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185069((5S,6S,7S)-5-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataKi:  6.70E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185061((4R,5S,7R)-5-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataKi:  8.50E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185060((7S,8R)-7-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185064((5S,6S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185072((5S,6S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185067((4R,5S,7R)-5-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185071((5S,6S,7S)-5-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185070((4R,5S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185063((6S,7S)-7-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185065((4R,5S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180551(2-(3,5-bis(trifluoromethyl)benzyloxy)-6-fluoro-6-(...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314371((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50:  0.0130nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220124(1-(4-((3S,4R)-3-(5-(2-(3,5-bis(trifluoromethyl)phe...)
Affinity DataIC50:  0.0300nMAssay Description:Displacement of [125I]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314389((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50:  0.0410nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220132((3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-ac...)
Affinity DataIC50:  0.0500nMAssay Description:Displacement of [125I]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220121((3R,4S)-N-(2-(3,5-bis(trifluoromethyl)phenyl)propa...)
Affinity DataIC50:  0.0500nMAssay Description:Displacement of [125I]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218239((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313627((6R,7S,7aS)-2-amino-6-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50234162((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50327374((1S,2R,5aS,7S,8aR,8bS)-2-((R)-1-(3,5-bis(trifluoro...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313630((6R,7S,7aS)-2-((1H-pyrazol-5-yl)methylamino)-6-((R...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50372480(CHEMBL270090)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [125I]L-703606 from human NK1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50234162((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [125I]L-703606 from human NK1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50234162((6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phen...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 370 total ) | Next | Last >>
Jump to: