Compile Data Set for Download or QSAR
maximum 50k data
Found 26 with Last Name = 'whitson' and Initial = 'el'
TargetProtein kinase C zeta type(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50252375(CHEMBL446072 | Spheciosterol sulfate C)
Affinity DataIC50:  110nMAssay Description:Inhibition of PKCzeta (unknown origin) by TR-FRET based lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50252374(CHEMBL475118 | Spheciosterol sulfate B)
Affinity DataIC50:  530nMAssay Description:Inhibition of PKCzeta (unknown origin) by TR-FRET based lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50252376(CHEMBL455091 | Topsentiasterol sulfate E)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of PKCzeta (unknown origin) by TR-FRET based lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50252373(CHEMBL447723 | Spheciosterol sulfate A)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of PKCzeta (unknown origin) by TR-FRET based lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50340946((1R,3S,14S)-6,10,14-trimethyl-3-(prop-1-en-2-yl)-1...)
Affinity DataEC50:  1.08E+5nMAssay Description:Inhibition of HIF-2alpha activity in human 786-O cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50340947((6R,8S,18R)-3,8,12,16-Tetramethyl-7,18-dioxa-tricy...)
Affinity DataEC50:  1.83E+5nMAssay Description:Inhibition of HIF-2alpha activity in human 786-O cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50340948((1E,3E,7R*,8R*,11E)-1-(2-methoxypropan-2-yl)-4,8,1...)
Affinity DataEC50:  1.49E+5nMAssay Description:Inhibition of HIF-2alpha activity in human 786-O cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50340949((1R,2S)-1-((1R,4aS,11aR)-1-acetoxy-7-methyl-11-met...)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of HIF-2alpha activity in human 786-O cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50398331(MIMOSAMYCIN)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50340951((1R,2S)-1-((1R,4aS,8S,11aR)-1-acetoxy-8-hydroperox...)
Affinity DataEC50:  1.18E+4nMAssay Description:Inhibition of HIF-2alpha activity in human 786-O cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50356012(AAPTAMINE)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50398322(HETERONEMIN)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50398323(CHEMBL508487)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50398324(CHEMBL510804)
Affinity DataEC50:  4.20E+3nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50398325(CHEMBL2177350)
Affinity DataEC50:  8.70E+3nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50398326(CHEMBL2177349)
Affinity DataEC50:  1.48E+4nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50398327(VARIOLIN B)
Affinity DataEC50:  700nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50240865((4aS,6aS,12aR,12bS)-10-Hydroxy-4,4,6a,12b-tetramet...)
Affinity DataEC50:  3.30E+3nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50398328(CHEMBL2177348)
Affinity DataEC50:  2.70E+3nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50398329(CHEMBL2177347)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50398330(XESTOQUINONE)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50252374(CHEMBL475118 | Spheciosterol sulfate B)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NFkappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50252375(CHEMBL446072 | Spheciosterol sulfate C)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NFkappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50252376(CHEMBL455091 | Topsentiasterol sulfate E)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NFkappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50252373(CHEMBL447723 | Spheciosterol sulfate A)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NFkappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50340950((1R,2S)-1-((1R,4aS,9R,11aR)-1-acetoxy-9-hydroxy-7-...)
Affinity DataEC50:  6.20E+3nMAssay Description:Inhibition of HIF-2alpha activity in human 786-O cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed