Affinity DataKi: 1nM ΔG°: -51.4kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -51.4kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.7kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.7kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.5kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.5kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -46.9kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -46.5kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -46.9kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 10nM ΔG°: -45.7kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 11nM ΔG°: -45.0kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 13nM ΔG°: -45.0kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 15nM ΔG°: -44.2kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 16nM ΔG°: -44.5kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 24nM ΔG°: -43.1kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 40nM ΔG°: -42.2kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 47nM ΔG°: -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 50nM ΔG°: -41.7kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 53nM ΔG°: -41.5kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -41.2kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 63nM ΔG°: -41.1kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 72nM ΔG°: -40.8kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 82nM ΔG°: -40.4kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 82nM ΔG°: -40.4kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 90nM ΔG°: -39.8kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 109nM ΔG°: -39.3kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 112nM ΔG°: -39.3kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 160nM ΔG°: -38.8kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 163nM ΔG°: -38.4kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 165nM ΔG°: -38.3kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 170nM ΔG°: -38.2kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 285nM ΔG°: -37.0kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 314nM ΔG°: -36.7kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 320nM ΔG°: -37.1kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 534nM ΔG°: -35.4kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 782nM ΔG°: -34.5kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nM ΔG°: -33.5kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 2.06E+3nM ΔG°: -32.5kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nM ΔG°: -31.3kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 3.23E+3nM ΔG°: -31.0kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 3.67E+3nM ΔG°: -30.7kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 4.16E+3nM ΔG°: -30.4kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 1.06E+4nM ΔG°: -28.4kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
Affinity DataKi: >1.58E+4nM ΔG°: >-27.1kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3.98nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 5.01nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6.31nMAssay Description:Inhibition of IKK1 in presence of 1 uM ATPMore data for this Ligand-Target Pair