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Found 35 with Last Name = 'whitworth' and Initial = 'jm'
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160371(7-Methoxy-6-oxazol-5-yl-3-(2-pyridin-4-yl-ethyl)-2...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160379(7-Methoxy-3-methyl-6-oxazol-5-yl-2-thioxo-2,3-dihy...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160378(3-(3-Imidazol-1-yl-propyl)-7-methoxy-6-oxazol-5-yl...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160375(7-Methoxy-6-oxazol-5-yl-2-thioxo-2,3-dihydro-1H-qu...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174783(1-tert-butyl 5-methyl (3S,5R)-7'-methoxy-3'-methyl...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174782(CHEMBL198729 | N,N-diethyl-7'-methoxy-3'-methyl-6'...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160374(3-[2-(1H-Imidazol-4-yl)-ethyl]-7-methoxy-6-oxazol-...)
Affinity DataIC50:  47nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174790(7-methoxy-2,3-dimethyl-6-(oxazol-5-yl)-2-styryl-2,...)
Affinity DataIC50:  49nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174792(CHEMBL199075 | N-(2,4-difluorophenyl)-7'-methoxy-N...)
Affinity DataIC50:  51nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174796(7'-methoxy-N,3'-dimethyl-6'-(1,3-oxazol-5-yl)-4'-o...)
Affinity DataIC50:  64nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174795(7'-methoxy-3'-methyl-6'-(1,3-oxazol-5-yl)-1-[(pipe...)
Affinity DataIC50:  68nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174789(7'-methoxy-3'-methyl-6'-(1,3-oxazol-5-yl)-4'-oxo-N...)
Affinity DataIC50:  71nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160368(7-Methoxy-3-(2-morpholin-4-yl-ethyl)-6-oxazol-5-yl...)
Affinity DataIC50:  71nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174785(CHEMBL372753 | N,7'-dimethoxy-N,3'-dimethyl-6'-(1,...)
Affinity DataIC50:  79nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174791(CHEMBL197163 | ethyl 7'-methoxy-3'-methyl-6'-(1,3-...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160370(3-(2-Imidazol-1-yl-ethyl)-7-methoxy-6-oxazol-5-yl-...)
Affinity DataIC50:  86nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160372(7-Methoxy-6-oxazol-5-yl-3-(2-pyridin-2-yl-ethyl)-2...)
Affinity DataIC50:  91nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174788(1-(2,2-dimethylpropanoyl)-7'-methoxy-3'-methyl-6'-...)
Affinity DataIC50:  94nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174781(7'-methoxy-3'-methyl-6'-(1,3-oxazol-5-yl)-3',4',1,...)
Affinity DataIC50:  96nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160373(7-Methoxy-6-oxazol-5-yl-3-pyridin-4-ylmethyl-2-thi...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160367(7-Methoxy-3-methyl-6-oxazol-5-yl-1H-quinazoline-2,...)
Affinity DataIC50:  104nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160367(7-Methoxy-3-methyl-6-oxazol-5-yl-1H-quinazoline-2,...)
Affinity DataIC50:  104nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174793(CHEMBL371533 | tert-butyl 7'-methoxy-6'-(1,3-oxazo...)
Affinity DataIC50:  104nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174798(CHEMBL373029 | N-ethyl-7'-methoxy-3'-methyl-6'-(1,...)
Affinity DataIC50:  119nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160369(7-Methoxy-6-oxazol-5-yl-3-(2-pyridin-4-yl-ethyl)-1...)
Affinity DataIC50:  188nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174786(7-methoxy-2,2,3-trimethyl-6-(oxazol-5-yl)-2,3-dihy...)
Affinity DataIC50:  192nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160380(7-Methoxy-3-(2-morpholin-4-yl-ethyl)-6-oxazol-5-yl...)
Affinity DataIC50:  297nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174780(7-methoxy-2,2-dimethyl-6-(oxazol-5-yl)-3-(2-(pyrid...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174784(7'-methoxy-3'-methyl-6'-(1,3-oxazol-5-yl)-1'H-spir...)
Affinity DataIC50:  328nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174799(1-tert-butyl 5-methyl (3S,5S)-7'-methoxy-3'-methyl...)
Affinity DataIC50:  369nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174797(7'-methoxy-3'-methyl-6'-(1,3-oxazol-5-yl)-4'-oxo-N...)
Affinity DataIC50:  393nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174787(7'-methoxy-3'-methyl-6'-(1,3-oxazol-5-yl)-2,3,5,6-...)
Affinity DataIC50:  526nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160377(3-(2,2-Dimethyl-propyl)-7-methoxy-6-oxazol-5-yl-2-...)
Affinity DataIC50:  821nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50174794(1-tert-butyl 5-methyl (3R,5S)-7'-methoxy-3'-methyl...)
Affinity DataIC50:  948nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D

Curated by ChEMBL
LigandPNGBDBM50160376(7-Methoxy-6-oxazol-5-yl-3-pyridin-3-yl-2-thioxo-2,...)
Affinity DataIC50:  1.71E+3nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed