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Found 33 with Last Name = 'widdowson' and Initial = 'j'
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051875((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051879((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281085((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory activity of compound was measured against Candida squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051872((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281078((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051874((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051866((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051867((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051864((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051872((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051878((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051871((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  65nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281084((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  134nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281077((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281079((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  355nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051868((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  395nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281074((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: >500nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051870((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281081((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: >500nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281083((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: >500nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281080((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: >500nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281075((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: >500nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051877((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051876((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051869((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50051865((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281073(Squalestatin analog | [(3E,7E)-4,8,12-trimethyltri...)
Affinity DataIC50:  8.70E+3nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50059865(4,8,12-trimethyl-(3E,7E)-3,7,11-tridecatrienylhydr...)
Affinity DataIC50:  3.15E+4nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281076(Squalestatin analog | {[(4E,8E)-5,9,13-trimethylte...)
Affinity DataIC50:  3.15E+4nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50281082((Hydroxy-methoxy-phosphorylmethyl)-((3E,7E)-4,8,12...)
Affinity DataIC50:  1.77E+5nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article