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Found 42 with Last Name = 'wiederrecht' and Initial = 'g'
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287769(17-ethyl-1,14,20-trihydroxy-12-[2-(4-hydroxy-3-met...)
Affinity DataIC50:  0.700nMAssay Description:Compound was evaluated in vitro for the competitive binding to FK506 binding protein 12 versus tritiated FK-506.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287770(17-allyl-1,14-dihydroxy-12-[2-(4-hydroxy-3-methoxy...)
Affinity DataIC50:  0.800nMAssay Description:Compound was evaluated in vitro for the competitive binding to FK506 binding protein 12 versus tritiated FK-506.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287766(17-ethyl-1,14-dihydroxy-12-[2-(4-hydroxy-3-methoxy...)
Affinity DataIC50:  1.60nMAssay Description:Compound was evaluated in vitro for the competitive binding to FK506 binding protein 12 versus tritiated FK-506.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079775(17-Ethyl-1,14-dihydroxy-12-{2-[4-(2-hydroxy-2-naph...)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287767(17-ethyl-1,14,20-trihydroxy-22,24-dimethoxy-12-[2-...)
Affinity DataIC50:  2.80nMAssay Description:Compound was evaluated in vitro for the competitive binding to FK506 binding protein 12 versus tritiated FK-506.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287771(17-ethyl-1,14-dihydroxy-22,24-dimethoxy-12-[2-[3-m...)
Affinity DataIC50:  3.60nMAssay Description:Compound was evaluated in vitro for the competitive binding to FK506 binding protein 12 versus tritiated FK-506.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079784(12-{2-[4-(2-Benzo[b]thiophen-2-yl-2-hydroxy-ethoxy...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079783(12-{2-[4-(2-Benzo[b]thiophen-2-yl-2-hydroxy-ethoxy...)
Affinity DataIC50:  4.20nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079776(17-Ethyl-1,14-dihydroxy-12-(2-{4-[2-hydroxy-2-(3-t...)
Affinity DataIC50:  4.90nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287765(17-ethyl-1,14-dihydroxy-12-[2-[4-(1H-5-indolyloxy)...)
Affinity DataIC50:  5.10nMAssay Description:Compound was evaluated in vitro for the competitive binding to FK506 binding protein 12 versus tritiated FK-506.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079782(17-Ethyl-1,14-dihydroxy-12-(2-{4-[2-hydroxy-2-(3-t...)
Affinity DataIC50:  5.90nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079770(C32-O-Phenalkyl ether derivative of Ascomycin | CH...)
Affinity DataIC50:  7.20nMAssay Description:Concentration required for inhibition of serine/threonine protein phosphatase calcineurin (CAN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079779(17-Ethyl-1,14-dihydroxy-12-{2-[4-(2-hydroxy-2-naph...)
Affinity DataIC50:  7.30nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079778(12-(2-{4-[2-(3,4-Difluoro-phenyl)-2-hydroxy-ethoxy...)
Affinity DataIC50:  7.30nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079780(12-(2-{4-[2-(3,5-Dimethyl-phenyl)-2-hydroxy-ethoxy...)
Affinity DataIC50:  7.90nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079781(12-(2-{4-[2-(3,4-Difluoro-phenyl)-2-hydroxy-ethoxy...)
Affinity DataIC50:  8.70nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079774(12-(2-{4-[2-(3,5-Dimethyl-phenyl)-2-hydroxy-ethoxy...)
Affinity DataIC50:  8.70nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287768(17-ethyl-1,14-dihydroxy-22,24-dimethoxy-12-[2-[3-m...)
Affinity DataIC50:  10nMAssay Description:Compound was evaluated in vitro for the competitive binding to FK506 binding protein 12 versus tritiated FK-506.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079767(C32-O-Phenalkyl ether derivative of Ascomycin | C3...)
Affinity DataIC50:  14nMAssay Description:Concentration required for inhibition of serine/threonine protein phosphatase calcineurin (CAN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079777((E)-(1R,9S,12S,13R,14R,21S,23S,24R,25S,27R)-17-All...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287764(17-ethyl-1,14-dihydroxy-22,24-dimethoxy-12-[2-[3-m...)
Affinity DataIC50:  75nMAssay Description:Compound was evaluated in vitro for the competitive binding to FK506 binding protein 12 versus tritiated FK-506.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079778(12-(2-{4-[2-(3,4-Difluoro-phenyl)-2-hydroxy-ethoxy...)
Affinity DataEC50:  7.5nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079777((E)-(1R,9S,12S,13R,14R,21S,23S,24R,25S,27R)-17-All...)
Affinity DataEC50:  0.900nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079784(12-{2-[4-(2-Benzo[b]thiophen-2-yl-2-hydroxy-ethoxy...)
Affinity DataEC50:  11nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079775(17-Ethyl-1,14-dihydroxy-12-{2-[4-(2-hydroxy-2-naph...)
Affinity DataEC50:  21nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079783(12-{2-[4-(2-Benzo[b]thiophen-2-yl-2-hydroxy-ethoxy...)
Affinity DataEC50:  12nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079782(17-Ethyl-1,14-dihydroxy-12-(2-{4-[2-hydroxy-2-(3-t...)
Affinity DataEC50:  45nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079780(12-(2-{4-[2-(3,5-Dimethyl-phenyl)-2-hydroxy-ethoxy...)
Affinity DataEC50:  7.5nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079774(12-(2-{4-[2-(3,5-Dimethyl-phenyl)-2-hydroxy-ethoxy...)
Affinity DataEC50:  9nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079776(17-Ethyl-1,14-dihydroxy-12-(2-{4-[2-hydroxy-2-(3-t...)
Affinity DataEC50:  45nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079781(12-(2-{4-[2-(3,4-Difluoro-phenyl)-2-hydroxy-ethoxy...)
Affinity DataEC50:  14nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079779(17-Ethyl-1,14-dihydroxy-12-{2-[4-(2-hydroxy-2-naph...)
Affinity DataEC50:  18nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079770(C32-O-Phenalkyl ether derivative of Ascomycin | CH...)
Affinity DataEC50:  9.20nMAssay Description:Effective concentration determined was towards FK506 binding protein 12 by competitive binding assay using [3H]-dihydro FK-506 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50068939((E)-(9S,12S,13R,14S,17R,21S,23S,24R,25S,27S)-17-Et...)
Affinity DataEC50:  1.60nMAssay Description:Effective concentration determined was towards FK506 binding protein 12 by competitive binding assay using [3H]-dihydro FK-506 as radioligandMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079765(C32-O-Phenalkyl ether derivative of Ascomycin | C3...)
Affinity DataEC50:  5.30nMAssay Description:Effective concentration determined was towards FK506 binding protein 12 by competitive binding assay using [3H]-dihydro FK-506 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079767(C32-O-Phenalkyl ether derivative of Ascomycin | C3...)
Affinity DataEC50:  32nMAssay Description:Effective concentration determined was towards FK506 binding protein 12 by competitive binding assay using [3H]-dihydro FK-506 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079766(17-Ethyl-1,14-dihydroxy-23,25-dimethoxy-12-[2-(3-m...)
Affinity DataEC50:  12nMAssay Description:Effective concentration determined was towards FK506 binding protein 12 by competitive binding assay using [3H]-dihydro FK-506 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071465(Ascomycin derivative | CHEMBL428499)
Affinity DataEC50:  22nMAssay Description:Binding affinity of the compound for FK506 binding protein 12 using [3H]-dihydro FK-506 radioligand was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071466(Ascomycin derivative | CHEMBL386482)
Affinity DataEC50:  7.40nMAssay Description:Binding affinity of the compound for FK506 binding protein 12 using [3H]-dihydro FK-506 radioligand was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50068939((E)-(9S,12S,13R,14S,17R,21S,23S,24R,25S,27S)-17-Et...)
Affinity DataEC50:  1.60nMAssay Description:Binding affinity of the compound for FK506 binding protein 12 using [3H]-dihydro FK-506 radioligand was determinedMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071450(Ascomycin derivative | CHEMBL385568)
Affinity DataEC50:  12nMAssay Description:Binding affinity of the compound for FK506 binding protein 12 using [3H]-dihydro FK-506 radioligand was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071463(Ascomycin derivative | C32-O-cinnamyl ether analog...)
Affinity DataEC50:  30nMAssay Description:Binding affinity of the compound for FK506 binding protein 12 using [3H]-dihydro FK-506 radioligand was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed