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Found 83 with Last Name = 'wiedmer' and Initial = 'l'
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50152124(CHEMBL3782004)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50117930((4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of fluorescently labeled tracer binding to human ERG by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524490(CHEMBL4561244)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524491(CHEMBL4446950)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524489(CHEMBL4541864)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148556(CHEMBL3770322)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148554(CHEMBL3770598)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524488(CHEMBL4589188)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148555(CHEMBL3771341)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148570(CHEMBL3770330)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148569(CHEMBL3770969)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148553(CHEMBL3769500)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148565(CHEMBL3771234)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148567(CHEMBL3771132)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148552(CHEMBL3770150)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148568(CHEMBL3769504)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148566(CHEMBL3771036)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543337(CHEMBL4633281)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524493(CHEMBL4448755)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524487(CHEMBL1232596)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50324898(3-(2-amino-5-chloro-1H-benzimidazol-1-yl)propan-1-...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148562(CHEMBL3770890)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7960(1H-1,3-benzodiazol-2-amine | 2-Aminobenzimidazole ...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50372980(CHEMBL404150)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148559(CHEMBL3770026)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148564(CHEMBL3771157)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543334(CHEMBL4640946)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543329(CHEMBL4645614)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148563(CHEMBL3771223)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148561(CHEMBL3769540)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50148560(CHEMBL3769841)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant GST-tagged CREBBP using non acetylated ligand 1 as substrate incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524492(CHEMBL4476663)
Affinity DataIC50:  1.23E+5nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM16223(1H-pyrrolo[2,3-b]pyridine | 7-azaindole | compound...)
Affinity DataIC50:  1.32E+5nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543323(CHEMBL4639014)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543328(CHEMBL4640214)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543327(CHEMBL4632838)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543326(CHEMBL4639771)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543325(CHEMBL4636323)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543322(CHEMBL4648078)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543338(CHEMBL4636300)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543324(CHEMBL4649595)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543336(CHEMBL4642942)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543335(CHEMBL4640010)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543330(CHEMBL4635290)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543331(CHEMBL4640849)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543332(CHEMBL4645095)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543333(CHEMBL4640700)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524490(CHEMBL4561244)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of BACE1 (unknown origin) using HiLyte Fluo488/QXL-520 as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524488(CHEMBL4589188)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of BACE1 (unknown origin) using HiLyte Fluo488/QXL-520 as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50543321(CHEMBL4646098)
Affinity DataIC50:  3.36E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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