Affinity DataIC50: 13nMAssay Description:Competitive inhibition of androgen binding to androgen receptor (unknown origin) by invitrogen polar screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced KLK2 gene expression by Array Plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced KLK2 gene expression by Array Plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced KLK3 gene expression by Array Plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced SPDEF gene expression by Array Plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced SPDEF gene expression by Array Plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced KLK3 gene expression by Array Plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced KLK2 gene expression by Array Plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced KLK2 gene expression by Array Plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced SPDEF gene expression by Array Plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.28E+3nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced SPDEF gene expression by Array Plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced KLK3 gene expression by Array Plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced KLK3 gene expression by Array Plate assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of SHP1 (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of PTP1B (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of TCPTP (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 3.12E+4nMAssay Description:Inhibition of p97 (unknown origin) ATPase activity after 10 mins by malachite green dye based visible spectrophotometryMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataEC50: 2.40E+4nMAssay Description:Inhibition of HSP90 in human MCF7 cells assessed as depletion of cell surface HER2 protein level after 18 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataEC50: 4.10E+4nMAssay Description:Inhibition of HSP90 in human MCF7 cells assessed as depletion of cell surface HER2 protein level after 18 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of HSP90 in human MCF7 cells assessed as depletion of cell surface HER2 protein level after 18 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataEC50: 3.80E+4nMAssay Description:Inhibition of HSP90 in human MCF7 cells assessed as depletion of cell surface HER2 protein level after 18 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataEC50: 2.00E+4nMAssay Description:Inhibition of HSP90 in human MCF7 cells assessed as depletion of cell surface HER2 protein level after 18 hrs by Western blot analysisMore data for this Ligand-Target Pair