Compile Data Set for Download or QSAR
maximum 50k data
Found 159 with Last Name = 'wild' and Initial = 'k'
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246690(Ac-WVTHRLAGLLSRSGGVVRKNFVPTDVGPFAF-NH2 | CHEMBL503...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246694(Ac-WVTHQLAGLLSQSGGVVRKNFVPTDVGPFAF-NH2 | CHEMBL524...)
Affinity DataIC50:  0.530nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246691(Ac-WVTH[Cit]LAGLLSRSGGVVRKNFVPTDVGPFAF-NH2 | CHEMB...)
Affinity DataIC50:  0.570nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246692(Ac-WVTHRLAGLLS[Cit]SGGVVRKNFVPTDVGPFAF-NH2 | CHEMB...)
Affinity DataIC50:  0.580nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246687(CHEMBL500283 | WVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2)
Affinity DataIC50:  0.640nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246689(Ac-VTHRLAGLLSRSGGVVRKNFVPTDVGPFAF-NH2 | CHEMBL5108...)
Affinity DataIC50:  0.710nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246709(Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGP[2-Nal...)
Affinity DataIC50:  0.790nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50025074(CHEMBL2372188)
Affinity DataIC50:  0.850nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50190350((1S,12R,14R)-5-hydroxy-10-methyl-14-propyltetracyc...)
Affinity DataIC50:  1nMAssay Description:Binding affinity to human recombinant ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246698(Ac-WVEHRLKGELSRKGGVV[hArg]KNFVPTDVGPFAF-NH2 | CHEM...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185859(9a-butyl-7-hydroxy-4-phenyl-1,2,9,9a-tetrahydroflu...)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50025097(CHEMBL2372192)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity to ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246697(Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGPFAF-NH...)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185836(9a-butyl-7-hydroxy-4-iodo-1,2,9,9a-tetrahydrofluor...)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPBP2A(Staphylococcus aureus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50217404(CHEMBL348278)
Affinity DataIC50:  1.40nMAssay Description:Compound was tested for its binding affinity towards Penicillin-binding protein 2a (PBP2a) using [13H]-benzylpenicillinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185867(9a-butyl-7-hydroxy-4-(trifluoromethyl)-1,2,9,9a-te...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185849((9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahyd...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185860(9a-butyl-7-hydroxy-4-propyl-1,2,9,9a-tetrahydroflu...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246710(Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGP[Bip]A...)
Affinity DataIC50:  1.60nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPBP2A(Staphylococcus aureus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50217406(CHEMBL351921)
Affinity DataIC50:  1.60nMAssay Description:Compound was tested for its binding affinity towards Penicillin-binding protein 2a (PBP2a) using [13H]-benzylpenicillinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185845(9a-butyl-7-hydroxy-4-(thiophen-2-yl)-1,2,9,9a-tetr...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246688(Ac-VTHRLAGLLSRSGGVVKNNFVPTDVGPFAF-NH2 | CHEMBL5093...)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246693(Ac-WVTH[Cit]LAGLLS[Cit]SGGVVRKNFVPTDVGPFAF-NH2 | C...)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246696(Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGP[1-Nal...)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185851((R,S)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahyd...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246701(Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVG[Thz]FA...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185859(9a-butyl-7-hydroxy-4-phenyl-1,2,9,9a-tetrahydroflu...)
Affinity DataIC50:  2nMAssay Description:Activity at human ERbeta transfected in HEK293 cells assessed as transactivation of alkaline phosphatase reporter geneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246695(Ac-WVTH[hArg]LAGLLS[hArg]SGGVVRKNFVPTDVGPFAF-NH2 |...)
Affinity DataIC50:  2.10nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246708(Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGP[1-Nal...)
Affinity DataIC50:  2.20nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50025073(CHEMBL2372187)
Affinity DataIC50:  2.20nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPBP2A(Staphylococcus aureus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50217407(CHEMBL161482)
Affinity DataIC50:  2.40nMAssay Description:Compound was tested for its binding affinity towards Penicillin-binding protein 2a (PBP2a) using [13H]-benzylpenicillinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185856(4-bromo-7-hydroxy-9a-phenyl-1,2,9,9a-tetrahydroflu...)
Affinity DataIC50:  2.5nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185839(9a-butyl-4-(furan-2-yl)-7-hydroxy-1,2,9,9a-tetrahy...)
Affinity DataIC50:  3.10nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246700(Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVG[Aib]FA...)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50025075(CHEMBL2372193)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50025076(CHEMBL2372194)
Affinity DataIC50:  3.60nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246704(Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVG[Sar]FA...)
Affinity DataIC50:  3.80nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50025095(CHEMBL2372190)
Affinity DataIC50:  4.20nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185843(4-bromo-7-hydroxy-9a-propyl-1,2,9,9a-tetrahydroflu...)
Affinity DataIC50:  4.40nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185855(4-bromo-9a-ethyl-7-hydroxy-1,2,9,9a-tetrahydrofluo...)
Affinity DataIC50:  4.5nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50000743(CHEMBL525571 | [Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Se...)
Affinity DataIC50:  4.90nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50246699(Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVG[Hyp]FA...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50190349((1S,12R,15R)-5-hydroxy-10-methyl-15-propyltetracyc...)
Affinity DataIC50:  5nMAssay Description:Binding affinity to human recombinant ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50190352((1S,12R,15R)-15-ethyl-5-hydroxy-10-methyltetracycl...)
Affinity DataIC50:  5nMAssay Description:Binding affinity to human recombinant ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185866(9a-butyl-4-chloro-7-hydroxy-1,2,9,9a-tetrahydroflu...)
Affinity DataIC50:  5.30nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPBP2A(Staphylococcus aureus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50217403(CHEMBL161759)
Affinity DataIC50:  7.10nMAssay Description:Compound was tested for its binding affinity towards Penicillin-binding protein 2a (PBP2a) using [13H]-benzylpenicillinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(RAT)
Amgen

Curated by ChEMBL
LigandPNGBDBM50246693(Ac-WVTH[Cit]LAGLLS[Cit]SGGVVRKNFVPTDVGPFAF-NH2 | C...)
Affinity DataIC50:  8.90nMAssay Description:Antagonist activity at rat CGRP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185845(9a-butyl-7-hydroxy-4-(thiophen-2-yl)-1,2,9,9a-tetr...)
Affinity DataIC50:  9nMAssay Description:Activity at human ERbeta transfected in HEK293 cells assessed as transactivation of alkaline phosphatase reporter geneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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