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Found 488 with Last Name = 'william' and Initial = 'ad'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400316(CHEMBL2181087)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400305(CHEMBL2181088)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50363198(CHEMBL1946006)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant Cdk2/cyclin A using RbING as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50384877(CHEMBL2035183)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50384868(CHEMBL2035049)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of recombinant FLT3 using poly(Glu,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400315(CHEMBL2181312)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50363199(CHEMBL1946150)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant Cdk2/cyclin A using RbING as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50363197(CHEMBL1946005)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant Cdk2/cyclin A using RbING as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50363202(CHEMBL1946442)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant Cdk2/cyclin A using RbING as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50384874(CHEMBL2035055)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant FLT3 using poly(Glu,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400303(CHEMBL2181311)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50363196(CHEMBL1944698)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant Cdk2/cyclin A using RbING as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315839(4-methyl-N-(3-(2-(6-methyl-5-(2-(thiophen-2-yl)ace...)
Affinity DataIC50:  13nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50384872(CHEMBL2035053)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400311(CHEMBL2181331)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400304(CHEMBL2181310)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50384869(CHEMBL2035050)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant FLT3 using poly(Glu,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315848(CHEMBL1090568 | N-(6-methyl-3-styryl-1H-indazol-5-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400304(CHEMBL2181310)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50384878(CHEMBL2035184)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400306(CHEMBL2181086)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant TYK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50363199(CHEMBL1946150)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50384871(CHEMBL2035052)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50362408(CHEMBL1940142)
Affinity DataIC50:  18nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400305(CHEMBL2181088)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400307(CHEMBL2181084)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50363198(CHEMBL1946006)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant Flt3 using poly(Glu,Tyr) as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315850(CHEMBL1091643 | N-(6-methyl-3-styryl-1H-indazol-5-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400302(CHEMBL2181313)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50363211(CHEMBL1947162)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant Cdk2/cyclin A using RbING as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400308(CHEMBL2181083)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400312(CHEMBL2181330)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50384882(CHEMBL2035044)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant CDK2 using RbING as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50384876(CHEMBL2035182)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant FLT3 using poly(Glu,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50363225(CHEMBL1945566)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant Cdk2/cyclin A using RbING as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400310(CHEMBL2181332)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315851(2-phenyl-N-(3-styryl-1H-indazol-5-yl)acetamide | C...)
Affinity DataIC50:  22nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50360580(CHEMBL1933343)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant Flt3 using poly(Glu,Tyr) as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400309(CHEMBL2181082)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50363197(CHEMBL1946005)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant Flt3 using poly(Glu,Tyr) as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400312(CHEMBL2181330)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50384877(CHEMBL2035183)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant FLT3 using poly(Glu,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50363222(CHEMBL1945051)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant Cdk2/cyclin A using RbING as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400313(CHEMBL2181329)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400315(CHEMBL2181312)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50362405(CHEMBL1940139)
Affinity DataIC50:  25nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50363224(CHEMBL1945565)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant Flt3 using poly(Glu,Tyr) as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400301(CHEMBL2181314)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400311(CHEMBL2181331)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315837(CHEMBL1091232 | N-(3-(3-((4-methylpiperazin-1-yl)m...)
Affinity DataIC50:  26nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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