Compile Data Set for Download or QSAR
maximum 50k data
Found 531 with Last Name = 'wilson' and Initial = 'ns'
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(CHEMBL233338 | N-(1-(3-aminopropyl)-5-(N-methylcyc...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50566082(CHEMBL4779359)
Affinity DataIC50:  29nMAssay Description:Inhibition of probe-5 binding to human TNFalpha (77 to 233 residues) at 1 nM by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212789(1-(5-amino-5-oxopentyl)-N-cyclohexyl-N-methyl-2-(t...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212761(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(o...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212770(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(n...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50566088(CHEMBL4793924)
Affinity DataIC50:  71nMAssay Description:Inhibition of probe-5 binding to human TNFalpha (77 to 233 residues) at 1 nM by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212760(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(4...)
Affinity DataIC50:  76nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212788(1-(3-amino-3-oxopropyl)-2-(4-bromobenzamido)-N-cyc...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212776(CHEMBL233365 | N-cyclohexyl-1-(3-hydroxypropyl)-N-...)
Affinity DataIC50:  92nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Mus musculus)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50566088(CHEMBL4793924)
Affinity DataIC50:  99nMAssay Description:Inhibition of TNFalpha in mouse L929 cells exposed to compound incubated for 1 hr with mouse TNFalpha by luminescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM384279(US10280184, Example G.1.1)
Affinity DataIC50: <100nMAssay Description:The CSF-1R construct corresponds to recombinant human catalytic domain (aa 538-910), which was purchased from Invitrogen (cat #PV4092). CSF-1R was mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM384280(US10280184, Example G.1.2 | US10280184, Example G....)
Affinity DataIC50: <100nMAssay Description:The CSF-1R construct corresponds to recombinant human catalytic domain (aa 538-910), which was purchased from Invitrogen (cat #PV4092). CSF-1R was mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM384281(US10280184, Example G.1.3)
Affinity DataIC50: <100nMAssay Description:The CSF-1R construct corresponds to recombinant human catalytic domain (aa 538-910), which was purchased from Invitrogen (cat #PV4092). CSF-1R was mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM384280(US10280184, Example G.1.2 | US10280184, Example G....)
Affinity DataIC50: <100nMAssay Description:The CSF-1R construct corresponds to recombinant human catalytic domain (aa 538-910), which was purchased from Invitrogen (cat #PV4092). CSF-1R was mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287412(US9567339, Example E.9.11)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287413(US9567339, Example E.9.12)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287414(US9567339, Example E.9.13)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287415(US9567339, Example E.9.14)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287416(US9567339, Example E.9.15)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287417(US9567339, Example E.9.16)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287418(US9567339, Example E.9.17)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287419(US9567339, Example E.9.18)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287420(US9567339, Example E.9.19)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287421(US9567339, Example E.9.20)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287422(US9567339, Example E.9.21)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287424(US9567339, Example E.9.23)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287425(US9567339, Example E.9.24)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287426(US9567339, Example E.9.25)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287427(US9567339, Example E.9.26)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287428(US9567339, Example E.9.27)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287429(US9567339, Example E.9.28)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287431(US9567339, Example E.9.30)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287433(US9567339, Example E.9.32)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287435(US9567339, Example E.9.34)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287436(US9567339, Example E.9.35)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287437(US9567339, Example E.9.36)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287438(US9567339, Example E.9.37)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287439(US9567339, Example E.9.38)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287449(US9567339, Example E.9.48)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287451(US9567339, Example E.9.50)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287457(US9567339, Example G.1.1)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287458(US9567339, Example G.1.2)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287459(US9567339, Example G.1.3)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287460(US9567339, Example H.1.1)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287461(US9567339, Example H.2.1)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM384217(US10280184, Example A.1.1)
Affinity DataIC50: <100nMAssay Description:The CSF-1R construct corresponds to recombinant human catalytic domain (aa 538-910), which was purchased from Invitrogen (cat #PV4092). CSF-1R was mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM384218(US10280184, Example A.1.2)
Affinity DataIC50: <100nMAssay Description:The CSF-1R construct corresponds to recombinant human catalytic domain (aa 538-910), which was purchased from Invitrogen (cat #PV4092). CSF-1R was mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM384219(US10280184, Example A.1.3)
Affinity DataIC50: <100nMAssay Description:The CSF-1R construct corresponds to recombinant human catalytic domain (aa 538-910), which was purchased from Invitrogen (cat #PV4092). CSF-1R was mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM384220(US10280184, Example A.1.4)
Affinity DataIC50: <100nMAssay Description:The CSF-1R construct corresponds to recombinant human catalytic domain (aa 538-910), which was purchased from Invitrogen (cat #PV4092). CSF-1R was mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM384221(US10280184, Example A.1.5)
Affinity DataIC50: <100nMAssay Description:The CSF-1R construct corresponds to recombinant human catalytic domain (aa 538-910), which was purchased from Invitrogen (cat #PV4092). CSF-1R was mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 531 total ) | Next | Last >>
Jump to: