Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of Cyclophilin A peptidyl-prolyl cis-trans isomerase activity (unknown origin) using Succ-Ala-Leu-Pro-Phe-p-nitroaniline as substrate by I...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibition of Cyclophilin A peptidyl-prolyl cis-trans isomerase activity (unknown origin) using Succ-Ala-Leu-Pro-Phe-p-nitroaniline as substrate by I...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Cyclophilin A peptidyl-prolyl cis-trans isomerase activity (unknown origin) using Succ-Ala-Leu-Pro-Phe-p-nitroaniline as substrate by I...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 144nMAssay Description:Inhibition of human recombinant BuChE using butyrylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 314nMAssay Description:Inhibition of human recombinant BuChE using butyrylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of human recombinant BuChE using butyrylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of human recombinant BuChE using butyrylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant BACE1 expressed in baculovirus system using panvera peptide as substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant BACE1 expressed in baculovirus system using M-2420 as substrate preincubated for 1 hr before substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human recombinant BuChE using butyrylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+3nMAssay Description:Inhibition of human recombinant BuChE using butyrylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of human recombinant BuChE using butyrylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant BACE1 expressed in baculovirus system using M-2420 as substrate preincubated for 1 hr before substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of human recombinant BuChE using butyrylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human recombinant AChE-induced amyloid beta (1-40) aggregation assessed as fibril formation after 24 hrs by thioflavin T-based fluorome...More data for this Ligand-Target Pair
Affinity DataIC50: 6.45E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.94E+5nMAssay Description:Inhibition of human recombinant BuChE using butyrylthiocholine iodide as substrate after 20 mins preincubation by Ellman methodMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataKd: 1.80nMAssay Description:Binding affinity to Cyclophilin A (unknown origin) at 0.625 nM to 10 uM by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataKd: 8.30nMAssay Description:Binding affinity to Cyclophilin B (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataKd: 570nMAssay Description:Binding affinity to Cyclophilin A (unknown origin) at 0.625 nM to 10 uM by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataKd: 5.80nMAssay Description:Binding affinity to Cyclophilin B (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataKd: 6nMAssay Description:Binding affinity to Cyclophilin A (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataKd: 2.10nMAssay Description:Binding affinity to Cyclophilin B (unknown origin) at 10 to 30 uM by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataKd: 4.5nMAssay Description:Binding affinity to Cyclophilin B (unknown origin) at 10 to 30 uM by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Chonnam National University
Curated by ChEMBL
Chonnam National University
Curated by ChEMBL
Affinity DataKd: 2.5nMAssay Description:Binding affinity to Cyclophilin A (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair