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Found 226 with Last Name = 'witherbee' and Initial = 'bj'
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128131((R)-3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-...)
Affinity DataIC50:  0.770nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in buffer with <1 nM [CETP] for 18 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human CETP-mediated transfer of [3H]-CE from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)
Affinity DataIC50:  20nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128175(1,1,1-Trifluoro-3-{[3-(3-isopropyl-phenoxy)-phenyl...)
Affinity DataIC50:  20nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128135(3-((3-(2,3-dichlorophenoxy)phenyl)(3-(1,1,2,2-tetr...)
Affinity DataIC50:  30nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128141(1,1,1-Trifluoro-3-{[3-(4-fluoro-phenoxy)-phenyl]-[...)
Affinity DataIC50:  30nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128164(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...)
Affinity DataIC50:  30nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128154(1,1,1-Trifluoro-3-{[3-(1,1,2,2-tetrafluoro-ethoxy)...)
Affinity DataIC50:  30nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128176(1,1,1-Trifluoro-3-{[3-(1,1,2,2-tetrafluoro-ethoxy)...)
Affinity DataIC50:  60nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128146(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(3-ethy...)
Affinity DataIC50:  60nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128136(3-((3-(3,5-dimethylphenoxy)phenyl)(3-(1,1,2,2-tetr...)
Affinity DataIC50:  70nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128131((R)-3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-...)
Affinity DataIC50:  73nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in hamster serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128167(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(3,4-di...)
Affinity DataIC50:  80nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128185(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(3-ethy...)
Affinity DataIC50:  80nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128131((R)-3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-...)
Affinity DataIC50:  80nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in rabbit serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128156(3-((3-(3,4-dichlorophenoxy)phenyl)(3-(1,1,2,2-tetr...)
Affinity DataIC50:  80nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128152(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(3-tert...)
Affinity DataIC50:  80nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128169(1,1,1-Trifluoro-3-{[3-(4-fluoro-3-methyl-phenoxy)-...)
Affinity DataIC50:  80nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128166(1,1,1-Trifluoro-3-{[3-(1,1,2,2-tetrafluoro-ethoxy)...)
Affinity DataIC50:  90nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128143(1,1,1-Trifluoro-3-[[3-(1,1,2,2-tetrafluoro-ethoxy)...)
Affinity DataIC50:  90nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128139(1,1,1-Trifluoro-3-{[3-(1,1,2,2-tetrafluoro-ethoxy)...)
Affinity DataIC50:  90nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128168(1,1,1-Trifluoro-3-[[3-(1,1,2,2-tetrafluoro-ethoxy)...)
Affinity DataIC50:  100nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128153(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(2,3-di...)
Affinity DataIC50:  100nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128162(1,1,1-Trifluoro-3-{[3-(1,1,2,2-tetrafluoro-ethoxy)...)
Affinity DataIC50:  100nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128148(1,1,1-Trifluoro-3-{[3-(3-fluoro-2-nitro-phenoxy)-p...)
Affinity DataIC50:  100nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094513(1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,2,2-...)
Affinity DataIC50:  140nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094513(1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,2,2-...)
Affinity DataIC50:  140nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128173(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...)
Affinity DataIC50:  200nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128177(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(cycloh...)
Affinity DataIC50:  200nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128132(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(3,5-di...)
Affinity DataIC50:  200nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128184(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(3-(dim...)
Affinity DataIC50:  200nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128165(1,1,1-Trifluoro-3-{[3-(1,1,2,2-tetrafluoro-ethoxy)...)
Affinity DataIC50:  200nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094513(1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,2,2-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human CETP-mediated transfer of [3H]-CE from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094513(1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,2,2-...)
Affinity DataIC50:  200nMAssay Description:In vitro human CETP inhibitory activity of the compound was assessed by measuring the rate of [3H]-cholesteryl ester ([3H]-CE) from HDL donor particl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128133(1,1,1-Trifluoro-3-{[3-(4-isopropyl-3-methyl-phenox...)
Affinity DataIC50:  200nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128138(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(benzyl...)
Affinity DataIC50:  200nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128155(1,1,1-Trifluoro-3-{[3-(4-propyl-phenoxy)-phenyl]-[...)
Affinity DataIC50:  200nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128183(1,1,1-Trifluoro-3-{(3-isopropoxy-phenyl)-[3-(1,1,2...)
Affinity DataIC50:  300nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128182(1,1,1-Trifluoro-3-{[3-(3-fluoro-phenoxy)-phenyl]-[...)
Affinity DataIC50:  300nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50118037(3-((3-cyclopentylbenzyl)(3-phenoxyphenyl)amino)-1,...)
Affinity DataIC50:  300nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128159(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(2-chlo...)
Affinity DataIC50:  300nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128145(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...)
Affinity DataIC50:  300nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128157(1,1,1-Trifluoro-3-{[3-(1,1,2,2-tetrafluoro-ethoxy)...)
Affinity DataIC50:  300nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50118045(1,1,1-Trifluoro-3-[(3-isopropoxy-benzyl)-(3-phenox...)
Affinity DataIC50:  350nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50118044(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...)
Affinity DataIC50:  390nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128171(1,1,1-Trifluoro-3-{[3-(1,1,2,2-tetrafluoro-ethoxy)...)
Affinity DataIC50:  400nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128180(1,1,1-Trifluoro-3-{[3-(2-nitro-phenoxy)-phenyl]-[3...)
Affinity DataIC50:  400nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128181(1,1,1-Trifluoro-3-{[3-(4-propoxy-phenoxy)-phenyl]-...)
Affinity DataIC50:  400nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128150(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(cyclop...)
Affinity DataIC50:  400nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128134(1,1,1-Trifluoro-3-{[3-(4-isopropyl-phenoxy)-phenyl...)
Affinity DataIC50:  400nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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