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Found 15 with Last Name = 'wolfe' and Initial = 'jl'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade Estadual Paulista (Unesp)

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  90nMAssay Description:Inhibition of Electric eel AChE assessed as amount of thiocholine released using acetylthiocholine iodide as substrate after 6 mins by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade Estadual Paulista (Unesp)

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Electric eel AChE assessed as amount of thiocholine released using acetylthiocholine iodide as substrate after 6 mins by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50401026(CHEMBL2204367)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human STAT6 expressed in 293-EBNA cells assessed as inhibition of IL4-induced STAT6 transcriptional activation after 1 hr by Photinus p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and transcription activator 6(Mus musculus)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50401026(CHEMBL2204367)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of mouse STAT6 expressed in BEAS2B cells assessed as IL4-induced eotaxin-3 secretion after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50401024(CHEMBL2204366)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human STAT6 expressed in 293-EBNA cells assessed as inhibition of IL4-induced STAT6 transcriptional activation after 1 hr by Photinus p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade Estadual Paulista (Unesp)

Curated by ChEMBL
LigandPNGBDBM50279525(CHEMBL4163934)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate measured during 6 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade Estadual Paulista (Unesp)

Curated by ChEMBL
LigandPNGBDBM50279524(CHEMBL4174584)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate measured during 6 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade Estadual Paulista (Unesp)

Curated by ChEMBL
LigandPNGBDBM50024206(3-[2-(dimethylamino)ethyl]-1H-indol-5-ol | 3-[2-(d...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of Electric eel AChE assessed as amount of thiocholine released using acetylthiocholine iodide as substrate after 6 mins by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade Estadual Paulista (Unesp)

Curated by ChEMBL
LigandPNGBDBM50448445(CHEMBL3125442)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of Electric eel AChE assessed as amount of thiocholine released using acetylthiocholine iodide as substrate after 6 mins by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade Estadual Paulista (Unesp)

Curated by ChEMBL
LigandPNGBDBM50038691(CHEMBL58579 | [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of Electric eel AChE assessed as amount of thiocholine released using acetylthiocholine iodide as substrate after 6 mins by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade Estadual Paulista (Unesp)

Curated by ChEMBL
LigandPNGBDBM50448444(CHEMBL3125443)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of Electric eel AChE assessed as amount of thiocholine released using acetylthiocholine iodide as substrate after 6 mins by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade Estadual Paulista (Unesp)

Curated by ChEMBL
LigandPNGBDBM30707(2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of Electric eel AChE assessed as amount of thiocholine released using acetylthiocholine iodide as substrate after 6 mins by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50401024(CHEMBL2204366)
Affinity DataKd:  701nMAssay Description:Binding affinity at human recombinant STAT6 by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50401025(CHEMBL2203687)
Affinity DataKd:  7.40E+4nMAssay Description:Binding affinity at human recombinant STAT6 by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50401026(CHEMBL2204367)
Affinity DataKd:  656nMAssay Description:Binding affinity at human recombinant STAT6 by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed