Compile Data Set for Download or QSAR
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Found 15 with Last Name = 'wright' and Initial = 'ae'
TargetCaspase-3(Homo sapiens (Human))
Harbor Branch Oceanographic Institution

Curated by ChEMBL
LigandPNGBDBM50478882(SECOBATZELLINE A)
Affinity DataIC50:  78.2nMAssay Description:Inhibition of peptidase activity of CPP32More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Harbor Branch Oceanographic Institution

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Cdc2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50127868(CHEMBL299895 | Sterol sulfate)
Affinity DataIC50:  480nMAssay Description:Binding affinity against Purinergic receptor P2Y12 using [3H]-2-methylthio-ADP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Harbor Branch Oceanographic Institution

Curated by ChEMBL
LigandPNGBDBM50478457(PLAKOLIDE A)
Affinity DataIC50:  723nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Harbor Branch Oceanographic Institution

Curated by ChEMBL
LigandPNGBDBM50478844(DISCORHABDIN | Discorhabdin P | Discorhabdine C)
Affinity DataIC50:  775nMAssay Description:Inhibition of CPP32 peptidase activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50127869(CHEMBL299307 | Sterol sulfate)
Affinity DataIC50:  2.20E+3nMAssay Description:Binding affinity against Purinergic receptor P2Y12 using [3H]-2-methylthio-ADP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Harbor Branch Oceanographic Institution

Curated by ChEMBL
LigandPNGBDBM50478883(Secobatzelline A Diacetate)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of peptidase activity of CPP32More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50316411(CHEMBL1094578 | gymnochrome F)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of MCL1 binding to Bak by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50220948(CID44435592 | Sch 725737 (1))
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of sodium channel NaV1.8 expressed in rat ND7/23 cells by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50316410(CHEMBL1094577 | gymnochrome E)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of human HDAC1 assessed as [3H]acetate release after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Harbor Branch Oceanographic Institution

Curated by ChEMBL
LigandPNGBDBM50269842(CHEMBL478797 | microxine)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of Cdc2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292440(Aplysiillin A | CHEMBL462733)
Affinity DataIC50:  2.00E+4nMAssay Description:Displacement of [125I]thrombin from thrombin receptor in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Harbor Branch Oceanographic Institution

Curated by ChEMBL
LigandPNGBDBM50478884(Secobatzelline B Diacetate)
Affinity DataIC50:  2.58E+4nMAssay Description:Inhibition of peptidase activity of CPP32More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50292412(34-sulfatobastadin 13 | CHEMBL465400)
Affinity DataIC50:  3.90E+4nMAssay Description:Displacement of [125]ET1 from ETA receptor in pig thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Harbor Branch Oceanographic Institution

Curated by ChEMBL
LigandPNGBDBM50478519(CHEMBL462734)
Affinity DataIC50:  4.45E+4nMAssay Description:Displacement of [3H]LTB4 from LTB4 receptor in human neutrophilsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed