Affinity DataIC50: 0.980nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity to human PPAR alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Binding affinity to human PPAR alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Binding affinity to human PPAR alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Binding affinity to human PPAR alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Binding affinity to human PPAR alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Antagonist activity at rat GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induc...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:In vitro binding affinity against human PPARalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Binding affinity to human PPAR alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair