Compile Data Set for Download or QSAR
maximum 50k data
Found 44 with Last Name = 'wu' and Initial = 'zj'
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620080(2-((2-ethyl-6-(5-fluoro-6-(3-hydroxyazetidin-1-car...)
Affinity DataIC50:  0nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620091((R)-2-(ethyl(2-ethyl-5-(2-(3-hydroxypyrrolidin-1-y...)
Affinity DataIC50:  3.80nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620072(2-((2-ethyl-6-(5-(3-hydroxyazetidin-1-carbonyl)pyr...)
Affinity DataIC50:  4.40nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620090((S5)-2-(ethyl(2-ethyl-5-(2-(3-hydroxypyrrolidin-1-...)
Affinity DataIC50:  4.60nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620067(2-((2-ethyl-6-(5-fluoro-6-(2-(3-hydroxyazetidin-1-...)
Affinity DataIC50:  5.20nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620089(2-(ethyl(2-ethyl-5-(2-(4-hydroxypiperidin-1-yl)pyr...)
Affinity DataIC50:  5.5nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620081(2-((5-(2-(1,1-dioxidoisothiazolidin-2-yl)pyrimidin...)
Affinity DataIC50:  7.40nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620085(2-((5-(2-(1,1-dioxido-1,2-thiazinan-2-yl)pyrimidin...)
Affinity DataIC50:  11nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620087(2-(ethyl(2-ethyl-5-(2-(3-(hydroxymethyl)azetidin-1...)
Affinity DataIC50:  11nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620086(2-(ethyl(2-ethyl-5-(2-(3-hydroxyazetidin-1-yl)pyri...)
Affinity DataIC50:  11nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620088(1-(5-(3-((5-cyano-4-(4-fluorophenyl)thiazol-2-yl)(...)
Affinity DataIC50:  12nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620077((R)-2-((2-ethyl-6-(5-(2-(3-hydroxypyrrolidin-1-yl)...)
Affinity DataIC50:  13nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620082(2-((5-(2-(1,1-dioxidoisothiazolidin-2-yl)pyrimidin...)
Affinity DataIC50:  15nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620083(2-((6-(5-(1,1-dioxidoisothiazolidin-2-yl)pyrazin-2...)
Affinity DataIC50:  17nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620074(2-((2-ethyl-6-(3-fluoro-5-(2-(3-hydroxyazetidin-1-...)
Affinity DataIC50:  18nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620076(2-((2-ethyl-6-(5-(2-(3-(hydroxymethyl)azetidin-1-y...)
Affinity DataIC50:  19nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620068(2-((2-ethyl-6-(5-(2-(3-hydroxyazetidin-1-yl)-2-oxo...)
Affinity DataIC50:  21nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620092(2-(ethyl(2-ethyl-5-(2-morpholinopyrimidin-5-yl)-2H...)
Affinity DataIC50:  23nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620071(2-((2-ethyl-6-(5-(2-(3-hydroxyazetidin-1-yl)-2-oxo...)
Affinity DataIC50:  25nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620075((S)-2-((2-ethyl-6-(5-(2-(3-hydroxypyrrolidin-1-yl)...)
Affinity DataIC50:  25nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620073(2-((2-ethyl-6-(5-(1-(3-hydroxyazetidin-1-yl)-2-met...)
Affinity DataIC50:  28nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620070(2-((2-ethyl-6-(6-(2-(3-hydroxyazetidin-1-yl)-2-oxo...)
Affinity DataIC50:  29nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620066(2-((2-ethyl-6-(6-(2-(3-hydroxyazetidin-1-yl)-2-oxo...)
Affinity DataIC50:  29nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620065(2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxo...)
Affinity DataIC50:  30nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620079(5-(3-((5-cyano-4-(4-fluorophenyl)thiazol-2-yl)(met...)
Affinity DataIC50:  40nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620078(2-(5-(3-((5-cyano-4-(4-fluorophenyl)thiazol-2-yl)(...)
Affinity DataIC50:  42nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620084(N-(5-(3-((5-cyano-4-(4-fluorophenyl)thiazol-2-yl)(...)
Affinity DataIC50:  45nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620069(2-((2-ethyl-6-(6-(2-(3-hydroxyazetidin-1-yl)-2-oxo...)
Affinity DataIC50:  48nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM50187686(CHEMBL3828074 | US10526329, Compound 2 | US1107261...)
Affinity DataIC50:  112nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035703(CHEMBL3343903)
Affinity DataIC50:  510nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035706(CHEMBL3343901)
Affinity DataIC50:  750nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035702(CHEMBL91933)
Affinity DataIC50:  890nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035704(CHEMBL3343902)
Affinity DataIC50:  2.39E+3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50229666((2S,3S)-2-((S)-1-((2S,3S)-2-amino-3-methylpentanoy...)
Affinity DataIC50:  2.53E+3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035708(CHEMBL3343899)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035707(CHEMBL3343900)
Affinity DataIC50:  2.81E+3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035705(CHEMBL90170)
Affinity DataIC50:  3.35E+3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620090((S5)-2-(ethyl(2-ethyl-5-(2-(3-hydroxypyrrolidin-1-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Rapid activation of human delayed rectifier potassium current (IKr) is mainly mediated by hERG ion channel and participates in repolarization of huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620092(2-(ethyl(2-ethyl-5-(2-morpholinopyrimidin-5-yl)-2H...)
Affinity DataIC50: >3.00E+4nMAssay Description:Rapid activation of human delayed rectifier potassium current (IKr) is mainly mediated by hERG ion channel and participates in repolarization of huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM50187686(CHEMBL3828074 | US10526329, Compound 2 | US1107261...)
Affinity DataIC50: >3.00E+4nMAssay Description:Rapid activation of human delayed rectifier potassium current (IKr) is mainly mediated by hERG ion channel and participates in repolarization of huma...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620081(2-((5-(2-(1,1-dioxidoisothiazolidin-2-yl)pyrimidin...)
Affinity DataIC50: >3.00E+4nMAssay Description:Rapid activation of human delayed rectifier potassium current (IKr) is mainly mediated by hERG ion channel and participates in repolarization of huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620089(2-(ethyl(2-ethyl-5-(2-(4-hydroxypiperidin-1-yl)pyr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Rapid activation of human delayed rectifier potassium current (IKr) is mainly mediated by hERG ion channel and participates in repolarization of huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035700(CHEMBL3343905)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50035701(CHEMBL3343904)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC substrate incubated for 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed