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Found 10 with Last Name = 'wyllie' and Initial = 's'
TargetTrypanothione synthetase(Trypanosoma cruzi)
University of Dundee

LigandPNGBDBM92592(DDD85811)
Affinity DataIC50:  95nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypanothione synthetase(Trypanosoma cruzi)
University of Dundee

LigandPNGBDBM92593(DDD86243)
Affinity DataIC50:  140nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypanothione synthetase(Trypanosoma cruzi)
University of Dundee

LigandPNGBDBM92590(DDD60632)
Affinity DataIC50:  273nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione synthetase(Trypanosoma cruzi)
University of Dundee

LigandPNGBDBM92591(DDD73385)
Affinity DataIC50:  317nMpH: 8.0 T: 2°CAssay Description:Hit compounds identified from the high throughput screen were also tested using orthogonal assay platform, namely the coupled assay described previou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50542902(CHEMBL4645906)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of MAOA (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)

Curated by ChEMBL
LigandPNGBDBM50575236(CHEMBL4874673)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 in pooled human liver microsomes using phenacetin as substrate preincubated for 30 mins in presence of NADPH followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)

Curated by ChEMBL
LigandPNGBDBM50575236(CHEMBL4874673)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 in pooled human liver microsomes using diclofenac as substrate preincubated for 30 mins in presence of NADPH followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)

Curated by ChEMBL
LigandPNGBDBM50575236(CHEMBL4874673)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19 in pooled human liver microsomes using (S)-(+)-mephenytoin as substrate preincubated for 30 mins in presence of NADPH followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)

Curated by ChEMBL
LigandPNGBDBM50575236(CHEMBL4874673)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 in pooled human liver microsomes using dextromethorphan as substrate preincubated for 30 mins in presence of NADPH followed by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Drugs For Neglected Diseases Initiative (Dndi)

Curated by ChEMBL
LigandPNGBDBM50575236(CHEMBL4874673)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in pooled human liver microsomes using midazolam or testosterone as substrate preincubated for 30 mins in presence of NADPH foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed