BindingDB PrimarySearch

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526622(CHEMBL4442827)

Ki: 0.0180nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50507816(Bms-986165 | Deucravacitinib)

Ki: 0.0200nMAssay Description:Inhibition of fluorescein labeled probe binding to His-tagged human TYK2 pseudokinase domain (575-869 residues) by Morrison titration based HTRF assa...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526613(CHEMBL4571920)

Ki: 0.0240nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526619(CHEMBL4439957)

Ki: 0.0350nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50530394(CHEMBL4561663)

Ki: 0.0600nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50530394(CHEMBL4561663)

Ki: 0.0600nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50519523(CHEMBL4440718)

Ki: 0.0700nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50519523(CHEMBL4440718)

Ki: 0.0700nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526615(CHEMBL4434711)

Ki: 0.0700nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526606(CHEMBL4532948 | US11174264, Compound I-3)

Ki: 0.0860nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324510(1-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl...)

Ki: 0.0860nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair

CHEMBL PC cid PC sid Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526624(CHEMBL4443010)

Ki: 0.0910nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526617(CHEMBL4435047)

Ki: 0.120nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526603(CHEMBL4293907)

Ki: 0.130nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526621(CHEMBL4438107)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526607(CHEMBL4474801)

Ki: 0.140nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526604(CHEMBL4561123)

Ki: 0.150nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324512(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl-N-...)

Ki: 0.190nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Dipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324523(CHEMBL1215018 | N-((3S)-1-(6-(aminomethyl)-5-(2,4-...)

Ki: 0.200nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavageMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526610(CHEMBL4453441)

Ki: 0.200nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526616(CHEMBL4579439)

Ki: 0.220nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526605(CHEMBL4438296)

Ki: 0.260nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324512(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl-N-...)

Ki: 0.270nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324510(1-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl...)

Ki: 0.280nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair

CHEMBL PC cid PC sid Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526611(CHEMBL4585272)

Ki: 0.290nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526612(CHEMBL4543066)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Dipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324525(6-(aminomethyl)-5-(2,4-dichlorophenyl)-N,7-dimethy...)

Ki: 0.300nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavageMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324511(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl-N-...)

Ki: 0.300nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526608(CHEMBL4547009)

Ki: 0.330nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526623(CHEMBL4466139 | US11174264, Compound I-4)

Ki: 0.340nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526618(CHEMBL4437714)

Ki: 0.380nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324500(1-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl...)

Ki: 0.400nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324524((6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylim...)

Ki: 0.420nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526609(CHEMBL4454109)

Ki: 0.480nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Dipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324524((6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylim...)

Ki: 0.5nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavageMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324504(6-(aminomethyl)-5-(2,4-dichlorophenyl)-N,7-dimethy...)

Ki: 0.550nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324513(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl-N-...)

Ki: 0.580nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Dipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324497((6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylim...)

Ki: 0.600nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavageMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324511(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl-N-...)

Ki: 0.600nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324500(1-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl...)

Ki: 0.600nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324508(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methyl-N-...)

Ki: 0.650nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324494(6-(aminomethyl)-5-(2,4-dichlorophenyl)-N-(1,3-dime...)

Ki: 0.700nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Dipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)

Ki: 0.700nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavageMore data for this Ligand-Target Pair

CHEMBL PC cid PC sid Patents

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Dipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)

Ki: 0.700nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavageMore data for this Ligand-Target Pair

CHEMBL PC cid PC sid Patents

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Dipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324504(6-(aminomethyl)-5-(2,4-dichlorophenyl)-N,7-dimethy...)

Ki: 0.700nMAssay Description:Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavageMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50526614(CHEMBL4517542)

Ki: 0.740nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50530395(CHEMBL4444178)

Ki: 0.800nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50530395(CHEMBL4444178)

Ki: 0.800nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

Dipeptidyl peptidase 9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50324524((6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylim...)

Ki: 0.830nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair