Affinity DataKi: 4.72nMAssay Description:Binding affinity to human 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: >1.40nMAssay Description:Displacement of 8-hydroxy-[3H]DPAT from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.35nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.04nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.22nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: >8.93nMAssay Description:Displacement of [3H]BRL-43694 from human recombinant 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 12.4nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 13.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 14.8nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 15.2nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 15.6nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 18.6nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 18.8nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of rat SGLT1More data for this Ligand-Target Pair
Affinity DataIC50: 22.1nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 23.7nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 24.4nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 24.6nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 24.6nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 26.7nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 27.8nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 28.4nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 30.1nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 32.3nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 32.7nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 36.1nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 36.4nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 36.4nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 37.3nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair