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Found 368 with Last Name = 'yoon' and Initial = 'do'
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294419(US9586959, Compound 98)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294378(US9586959, Compound 31)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294427(US9586959, Compound disclosed in WO 2010030785, Ex...)
Affinity DataIC50:  22nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294427(US9586959, Compound disclosed in WO 2010030785, Ex...)
Affinity DataIC50:  22nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50:  27nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at recombinant human histamine H4 receptor expressed in CHO-K1 cells assessed as inhibition of R-alpha-methylhistamine induced st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294418(US9586959, Compound 96)
Affinity DataIC50:  28nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294418(US9586959, Compound 96)
Affinity DataIC50:  28nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM22566(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)
Affinity DataIC50:  29nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294373(US9586959, Compound 104 | US9586959, Compound 24 |...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294386(US9586959, Compound 49)
Affinity DataIC50:  34nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294386(US9586959, Compound 49)
Affinity DataIC50:  34nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50:  35nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294373(US9586959, Compound 104 | US9586959, Compound 24 |...)
Affinity DataIC50:  36nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294361(US9586959, Compound 4)
Affinity DataIC50:  40nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294414(US9586959, Compound 92)
Affinity DataIC50:  42nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50:  44nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294377(US9586959, Compound 29)
Affinity DataIC50:  49nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294377(US9586959, Compound 29)
Affinity DataIC50:  52nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294415(US9586959, Compound 93)
Affinity DataIC50:  53nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294368(US9586959, Compound 18)
Affinity DataIC50:  55nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294361(US9586959, Compound 4)
Affinity DataIC50:  57nMAssay Description:Displacement of [3H]BRL 43694 from human recombinant 5-HT3 receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294408(US9586959, Compound 74)
Affinity DataIC50:  60nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294416(US9586959, Compound 94)
Affinity DataIC50:  62nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294416(US9586959, Compound 94)
Affinity DataIC50:  62nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294409(US9586959, Compound 75)
Affinity DataIC50:  64nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294368(US9586959, Compound 18)
Affinity DataIC50:  65nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294385(US9586959, Compound 48)
Affinity DataIC50:  65nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294415(US9586959, Compound 93)
Affinity DataIC50:  65nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294366(US9586959, Compound 16)
Affinity DataIC50:  65nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294364(US9586959, Compound 12)
Affinity DataIC50:  67nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294364(US9586959, Compound 12)
Affinity DataIC50:  67nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294382(US9586959, Compound 43)
Affinity DataIC50:  70nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294379(US9586959, Compound 32)
Affinity DataIC50:  73nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294361(US9586959, Compound 4)
Affinity DataIC50:  77nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294374(US9586959, Compound 25)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294362(US9586959, Compound 7)
Affinity DataIC50:  130nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294381(US9586959, Compound 39)
Affinity DataIC50:  130nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294373(US9586959, Compound 104 | US9586959, Compound 24 |...)
Affinity DataIC50:  130nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294362(US9586959, Compound 7)
Affinity DataIC50:  133nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294372(US9586959, Compound 23)
Affinity DataIC50:  140nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294383(US9586959, Compound 46)
Affinity DataIC50:  154nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294423(US9586959, Compound 110)
Affinity DataIC50:  160nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM50563967(CHEMBL4798729)
Affinity DataIC50:  170nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294380(US9586959, Compound 35)
Affinity DataIC50:  170nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294380(US9586959, Compound 35)
Affinity DataIC50:  170nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294367(US9586959, Compound 17)
Affinity DataIC50:  177nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294367(US9586959, Compound 17)
Affinity DataIC50:  180nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294387(US9586959, Compound 50)
Affinity DataIC50:  190nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294391(US9586959, Compound 54)
Affinity DataIC50:  200nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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