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Found 331 with Last Name = 'zhong' and Initial = 'q'
TargetEstrogen receptor(Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  0.410nMAssay Description:Displacement of fluormone-labeled ES2 from recombinant full length human ERalpha ligand binding domain expressed in insect cells after 2 hrs by TR-FR...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM50180684(4-OHT | Afimoxifene | TamoGel)
Affinity DataIC50:  0.530nMAssay Description:Displacement of fluormone-labeled ES2 from recombinant full length human ERalpha ligand binding domain expressed in insect cells after 2 hrs by TR-FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-PLGLDpaAR fluorescent substrate incubated for 2 hrs by microplate reader methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEstrogen receptor(Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM50210071(CHEMBL3885342)
Affinity DataIC50:  1.10nMAssay Description:Displacement of fluormone-labeled ES2 from recombinant full length human ERalpha ligand binding domain expressed in insect cells after 2 hrs by TR-FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476189(US10865384, Compound IM-39 | US10865384, Example 2...)
Affinity DataIC50:  2.70nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476192(US10865384, Compound IM-34 | US10865384, Example 2...)
Affinity DataIC50:  2.80nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataIC50:  3nMAssay Description:Displacement of fluoromone ligand from recombinant ER-alpha (unknown origin) by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476187(US10865384, Compound IM-37 | US10865384, Example 2...)
Affinity DataIC50:  3.20nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476188(US10865384, Compound IM-38 | US10865384, Example 2...)
Affinity DataIC50:  3.30nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476190(US10865384, Compound IM-40 | US10865384, Example 2...)
Affinity DataIC50:  3.70nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM50516760(CHEMBL4526356)
Affinity DataIC50:  4.10nMAssay Description:Displacement of fluoromone ligand from recombinant ER-alpha (unknown origin) by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50491733(CHEMBL2385554 | US10865384, Compound IM-26)
Affinity DataIC50:  4.30nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476191(US10865384, Compound IM-32 | US10865384, Example 2...)
Affinity DataIC50:  4.40nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50491730(CHEMBL2385555 | US10865384, Compound IM-19)
Affinity DataIC50:  4.70nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476185(US10865384, Compound IM-35 | US10865384, Example 2...)
Affinity DataIC50:  5nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476186(US10865384, Compound IM-36 | US10865384, Example 2...)
Affinity DataIC50:  5.30nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50600078(CHEMBL5171364)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-PLGLDpaAR fluorescent substrate incubated for 2 hrs by microplate reader methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476175(US10865384, Compound IM-31 | US10865384, Example 1...)
Affinity DataIC50:  6.40nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476175(US10865384, Compound IM-31 | US10865384, Example 1...)
Affinity DataIC50:  6.40nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476175(US10865384, Compound IM-31 | US10865384, Example 1...)
Affinity DataIC50:  6.70nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476175(US10865384, Compound IM-31 | US10865384, Example 1...)
Affinity DataIC50:  6.80nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476175(US10865384, Compound IM-31 | US10865384, Example 1...)
Affinity DataIC50:  6.80nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM50516760(CHEMBL4526356)
Affinity DataIC50:  7.80nMAssay Description:Downregulation of ER-alpha expression in human T47D cells measured after 5 days by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50491729(CHEMBL2385556 | US10865384, Compound IM-27)
Affinity DataIC50:  8.40nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataIC50:  8.5nMAssay Description:Downregulation of ER-alpha expression in human tamoxifen-resistant T47D cells over-expressing PKC-alpha measured after 5 days by Western blot analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataIC50:  9.30nMAssay Description:Downregulation of ER-alpha expression in human T47D cells measured after 5 days by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476184(US10865384, Compound IM-33 | US10865384, Example 2...)
Affinity DataIC50:  9.5nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476196(US10865384, Compound IM-43 | US10865384, Example 2...)
Affinity DataIC50:  11nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM50516760(CHEMBL4526356)
Affinity DataIC50:  13nMAssay Description:Downregulation of ER-alpha expression in human tamoxifen-resistant T47D cells over-expressing PKC-alpha measured after 5 days by Western blot analysi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM50090463(CHEMBL3581633)
Affinity DataIC50:  14nMAssay Description:Displacement of fluormone-labeled ES2 from recombinant full length human ERalpha ligand binding domain expressed in insect cells after 2 hrs by TR-FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476205(US10865384, Compound IM-18 | US10865384, Example 4...)
Affinity DataIC50:  14nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476177(US10865384, Compound IM-29 | US10865384, Example 1...)
Affinity DataIC50:  15nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476177(US10865384, Compound IM-29 | US10865384, Example 1...)
Affinity DataIC50:  15nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476177(US10865384, Compound IM-29 | US10865384, Example 1...)
Affinity DataIC50:  16nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476177(US10865384, Compound IM-29 | US10865384, Example 1...)
Affinity DataIC50:  16nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476206(US10865384, Compound IM-13 | US10865384, Example 4...)
Affinity DataIC50:  19nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476176(US10865384, Compound IM-30 | US10865384, Example 1...)
Affinity DataIC50:  20nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476207(US10865384, Compound IM-17 | US10865384, Example 4...)
Affinity DataIC50:  20nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50491728(CHEMBL2385557 | US10865384, Compound IM-4)
Affinity DataIC50:  20nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50:  22nMAssay Description:Inhibition of full length human PDE4D7 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50044784(CHEBI:79090 | SB-202190 | US10865384, Compound SB2...)
Affinity DataIC50:  24nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476182(US10865384, Compound IM-28 | US10865384, Example 2...)
Affinity DataIC50:  24nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM192501(US10865384, Compound SB203580 | US9187470, 104 (SB...)
Affinity DataIC50:  24nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476194(US10865384, Compound IM-42 | US10865384, Example 2...)
Affinity DataIC50:  26nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) autophosphorylation after 1 hrMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476176(US10865384, Compound IM-30 | US10865384, Example 1...)
Affinity DataIC50:  32nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476176(US10865384, Compound IM-30 | US10865384, Example 1...)
Affinity DataIC50:  32nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476176(US10865384, Compound IM-30 | US10865384, Example 1...)
Affinity DataIC50:  32nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476176(US10865384, Compound IM-30 | US10865384, Example 1...)
Affinity DataIC50:  32nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476208(US10865384, Compound IM-15 | US10865384, Example 4...)
Affinity DataIC50:  33nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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