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Found 177 with Last Name = 'van rietschoten' and Initial = 'k'
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256265(CHEMBL4089486)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256283(CHEMBL4079711)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256264(CHEMBL4099333)
Affinity DataKi:  0.140nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256277(CHEMBL4093698)
Affinity DataKi:  0.150nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256286(CHEMBL4076199)
Affinity DataKi:  0.210nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256262(CHEMBL4070056)
Affinity DataKi:  0.25nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256260(CHEMBL4094403)
Affinity DataKi:  0.360nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256276(CHEMBL4079260)
Affinity DataKi:  0.390nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256284(CHEMBL4075544)
Affinity DataKi:  0.400nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256288(CHEMBL4085408)
Affinity DataKi:  0.440nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538252(CHEMBL4642167)
Affinity DataKi:  0.540nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256283(CHEMBL4079711)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256263(CHEMBL4088185)
Affinity DataKi:  1.30nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538266(CHEMBL4649686)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538258(CHEMBL4641389)
Affinity DataKi:  2nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256277(CHEMBL4093698)
Affinity DataKi:  2nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256287(CHEMBL4105318)
Affinity DataKi:  2.10nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256284(CHEMBL4075544)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607211(CHEMBL5218456)
Affinity DataKi:  2.40nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607212(CHEMBL5220448)
Affinity DataKi:  2.40nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538270(CHEMBL4634220)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607222(CHEMBL5218740)
Affinity DataKi:  2.80nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538238(CHEMBL4642849)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256261(CHEMBL4059991)
Affinity DataKi:  3nMAssay Description:Inhibition of human plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538273(CHEMBL4634551)
Affinity DataKi:  3.10nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256261(CHEMBL4059991)
Affinity DataKi:  3.40nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein(Sus scrofa)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256277(CHEMBL4093698)
Affinity DataKi:  3.60nMAssay Description:Inhibition of pig plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538264(CHEMBL4636597)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607215(CHEMBL5220463)
Affinity DataKi:  4.90nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538274(CHEMBL4637644)
Affinity DataKi:  5.10nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538260(CHEMBL4643355)
Affinity DataKi:  5.20nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607219(CHEMBL5220631)
Affinity DataKi:  5.20nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538267(CHEMBL4634880)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256262(CHEMBL4070056)
Affinity DataKi:  5.5nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538272(CHEMBL4636032)
Affinity DataKi:  5.70nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538271(CHEMBL4648601)
Affinity DataKi:  5.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538239(CHEMBL4640044)
Affinity DataKi:  5.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607218(CHEMBL5220922)
Affinity DataKi:  6.10nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538263(CHEMBL4643893)
Affinity DataKi:  6.80nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607209(CHEMBL5219136)
Affinity DataKi:  8.80nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538259(CHEMBL4637500)
Affinity DataKi:  9nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607221(CHEMBL5220083)
Affinity DataKi:  9.70nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasma kallikrein(Rattus norvegicus)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50256276(CHEMBL4079260)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant Sprague-Dawley rat plasma kallikrein using fluorogenic H-Pro-Phe-Arg-AMC peptide as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607204(CHEMBL5219641)
Affinity DataKi:  12nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607178(CHEMBL5221012)
Affinity DataKi:  13nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607183(CHEMBL5220023)
Affinity DataKi:  13nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538265(CHEMBL4643498)
Affinity DataKi:  13nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607172(CHEMBL5220092)
Affinity DataKi:  14nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50538269(CHEMBL4635897)
Affinity DataKi:  15nMAssay Description:Binding affinity to 6x-His-tagged human EphA2 ecto-domain residues (Lys27 to Asn529 residues) expressed in HEK293 cells incubated for 60 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607194(CHEMBL5219400)
Affinity DataKi:  16nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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