Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 34 hits for monomerid = 10853,81341,81342,50173286,50257243,10853,81341,81342,50173286,50257243   

TargetEndochitinase B1(Neosartorya fumigata)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataKi:  17nMAssay Description:Inhibitory activity against Chitinase B1 (AfChiB1) using fuorometric assay with 4-methylumbelliferyl-b-D-N,N0-diacetylchitobiose as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChitinase A(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataIC50: 25nMAssay Description:Displacement of 4-methylumbelliferydiacetyl-chitobiose from Serratia marcescens ChiAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEndochitinase B1(Neosartorya fumigata)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataIC50: 27nMpH: 5.5Assay Description:Inhibition of argifin and other peptide derivatives against AfchiB1 and hCHT.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataIC50: 100nMAssay Description:Binding affinity to Serratia marcescens chitinase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEndochitinase B1(Neosartorya fumigata)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataKd:  460nMAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2006
Entry Details Article
PubMed
TargetChitinase A(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50257243(CHEMBL493316 | Dipeptide | N-acetyl-Arg{N(omega)-(...)
Affinity DataIC50: 750nMAssay Description:Displacement of 4-methylumbelliferydiacetyl-chitobiose from Serratia marcescens ChiAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEndochitinase B1(Neosartorya fumigata)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataIC50: 1.10E+3nMpH: 5.5 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2006
Entry Details Article
PubMed
TargetEndochitinase B1 [T138A](Aspergillus fumigatus)
University of Dundee

LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataKd:  1.21E+3nMAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2006
Entry Details Article
PubMed
TargetEndochitinase B1 [E322A](Aspergillus fumigatus)
University of Dundee

LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataKd:  1.37E+3nMAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2006
Entry Details Article
PubMed
TargetEndochitinase B1 [M243A](Aspergillus fumigatus)
University of Dundee

LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataKd:  1.73E+3nMAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2006
Entry Details Article
PubMed
TargetEndochitinase B1 [R301K](Aspergillus fumigatus)
University of Dundee

LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataKd:  2.16E+3nMAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2006
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50257243(CHEMBL493316 | Dipeptide | N-acetyl-Arg{N(omega)-(...)
Affinity DataIC50: 3.70E+3nMAssay Description:Displacement of 4-methylumbelliferydiacetyl-chitobiose from Serratia marcescens ChiBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50257243(CHEMBL493316 | Dipeptide | N-acetyl-Arg{N(omega)-(...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Serratia marcescens chitinase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetEndochitinase B1 [D175A](Aspergillus fumigatus)
University of Dundee

LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataKd:  3.81E+3nMAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2006
Entry Details Article
PubMed
TargetEndochitinase B1 [A217G](Aspergillus fumigatus)
University of Dundee

LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataKd:  4.24E+3nMAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2006
Entry Details Article
PubMed
TargetEndochitinase B1(Neosartorya fumigata)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM81341(Tetrapeptide)
Affinity DataIC50: 4.30E+3nMpH: 5.5Assay Description:Inhibition of argifin and other peptide derivatives against AfchiB1 and hCHT.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetChitotriosidase-1(Human)
University of Dundee

LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataIC50: 4.50E+3nMpH: 5.2 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2006
Entry Details Article
PubMed
TargetChitotriosidase-1(Human)
University of Dundee

LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataIC50: 4.50E+3nMpH: 5.5Assay Description:Inhibition of argifin and other peptide derivatives against AfchiB1 and hCHT.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetAcidic mammalian chitinase(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human acidic mammalian chitinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetEndochitinase B1(Neosartorya fumigata)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM81342(Tripeptide)
Affinity DataIC50: 5.10E+3nMpH: 5.5Assay Description:Inhibition of argifin and other peptide derivatives against AfchiB1 and hCHT.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Serratia marcescens chitinase ChiB assessed as reduction in chitinolytic activity using 4MU-(GlcNAc)2 substrate by fluorescence based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Serratia marcescens chitinase ChiBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Serratia marcescens chitinase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataIC50: 6.40E+3nMAssay Description:Displacement of 4-methylumbelliferydiacetyl-chitobiose from Serratia marcescens ChiBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Serratia marcescens chitinase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetEndochitinase B1(Neosartorya fumigata)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50257243(CHEMBL493316 | Dipeptide | N-acetyl-Arg{N(omega)-(...)
Affinity DataIC50: 1.20E+4nMpH: 5.5Assay Description:Inhibition of argifin and other peptide derivatives against AfchiB1 and hCHT.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetChitotriosidase-1(Human)
University of Dundee

LigandPNGBDBM81341(Tetrapeptide)
Affinity DataIC50: 2.80E+4nMpH: 5.5Assay Description:Inhibition of argifin and other peptide derivatives against AfchiB1 and hCHT.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetChitinase C1(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of 4-methylumbelliferydiacetyl-chitobiose from Serratia marcescens ChiCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitinase C1(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50257243(CHEMBL493316 | Dipeptide | N-acetyl-Arg{N(omega)-(...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of 4-methylumbelliferydiacetyl-chitobiose from Serratia marcescens ChiCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataKd:  3.30E+4nMAssay Description:Inhibition of Serratia marcescens chitinase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataKi:  3.30E+4nM ΔG°:  -6.36kcal/molepH: 5.5 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2006
Entry Details Article
PubMed
TargetChitotriosidase-1(Human)
University of Dundee

LigandPNGBDBM81342(Tripeptide)
Affinity DataIC50: 6.80E+4nMpH: 5.5Assay Description:Inhibition of argifin and other peptide derivatives against AfchiB1 and hCHT.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetChitotriosidase-1(Human)
University of Dundee

LigandPNGBDBM50257243(CHEMBL493316 | Dipeptide | N-acetyl-Arg{N(omega)-(...)
Affinity DataIC50: 1.90E+5nMpH: 5.5Assay Description:Inhibition of argifin and other peptide derivatives against AfchiB1 and hCHT.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetEndochitinase A1(Neosartorya fumigata)
University of Dundee

LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)
Affinity DataIC50: 3.80E+6nMpH: 5.5 T: 2°CAssay Description:Enzyme inhibition assay using chitinase A1 from aspergillus fumigatus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2011
Entry Details Article
PubMed