Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 120776,50272149,50273579,50273580,50273581,50326600,120776,50272149,50273579,50273580,50273581,50326600   

TargetGalectin-3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50272149(N-[(2R,3S,4R,5S,6S)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  33nMAssay Description:Binding affinity to galectin 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50326600(Di-(3,5-dimethoxybenzamido)-thiodigalactoside | CH...)
Affinity DataKd:  50nMAssay Description:Binding affinity to human galectin 3 at 20 degC by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetGalectin-3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50273581(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  160nMAssay Description:Competitive binding affinity to recombinant human galectin-3 after 5 mins in presence of fluorescent probe by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetGalectin-9(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273581(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  730nMAssay Description:Binding affinity to galectin 9N terminal domain at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-9(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273581(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  730nMAssay Description:Competitive binding affinity to recombinant human galectin-9 N-terminal after 5 mins in presence of fluorescent probe 2-(fluorescein-5-yl-carbonylami...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetGalectin-3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM120776(US8703720, 23)
Affinity DataKd:  1.40E+3nMAssay Description:Compounds 7, 15-19, and 22 were evaluated for their efficiency in inhibiting galectin-1 and galectin-3 in a known fluorescence polarization-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetGalectin-7(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273581(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to galectin 7 at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-7(Mouse)
Institute of Science Education and Research-Kolkata (Iiser) Kolkata

Curated by ChEMBL
LigandPNGBDBM50273581(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  1.70E+3nMAssay Description:Competitive binding affinity to recombinant mouse galectin-7 after 5 mins in presence of fluorescent probe beta-D-galactopyranosyl(1-4)-2- acetamido-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetGalectin-3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50273581(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to galectin 3 at 20 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-9(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273580(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to galectin 9N terminal domain at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-9(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50326600(Di-(3,5-dimethoxybenzamido)-thiodigalactoside | CH...)
Affinity DataKd:  1.82E+3nMAssay Description:Binding affinity to human galectin 9 N-terminal domain at 20 degC by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273580(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to galectin 1 at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-7(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273580(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to galectin 7 at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50273580(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to galectin 3 at 20 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGalectin-7(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50326600(Di-(3,5-dimethoxybenzamido)-thiodigalactoside | CH...)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to human galectin 7 at 4 degC by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetGalectin-7(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273579(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-4-benzami...)
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinity to galectin 7 at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50273579(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-4-benzami...)
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinity to galectin 3 at 20 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM120776(US8703720, 23)
Affinity DataKd:  6.30E+3nMAssay Description:Compounds 7, 15-19, and 22 were evaluated for their efficiency in inhibiting galectin-1 and galectin-3 in a known fluorescence polarization-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetGalectin-9(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273579(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-4-benzami...)
Affinity DataKd:  7.00E+3nMAssay Description:Binding affinity to galectin 9N terminal domain at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273581(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  9.60E+3nMAssay Description:Binding affinity to galectin 1 at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273581(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  9.60E+3nMAssay Description:Competitive binding affinity to recombinant human galectin-1 after 5 mins in presence of fluorescent probe 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273579(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-4-benzami...)
Affinity DataKd:  3.50E+4nMAssay Description:Binding affinity to galectin 1 at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-8(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273580(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to galectin 8N terminal domain at 20 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-8(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273581(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to galectin 8N terminal domain at 20 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-8(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50273581(N-[(2S,3R,4S,5R,6R)-2-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd: >1.00E+5nMAssay Description:Competitive binding affinity to recombinant human galectin-8 N-terminal after 5 mins in presence of fluorescent probe 2-(fluorescein-5-yl-carbonylami...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetGalectin-8(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50326600(Di-(3,5-dimethoxybenzamido)-thiodigalactoside | CH...)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to human galectin 8 N-terminal domain at 20 degC by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed