Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 15463,15464,15465,15466,15467,15468,15469,15463,15464,15465,15466,15467,15468,15469   

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

LigandPNGBDBM15465(4-[(3R)-3-{[2-(3,4-difluorophenyl)-2-oxoethyl]amin...)
Affinity DataIC50: 39nMpH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Eli Lilly

LigandPNGBDBM15464(4-[(3R)-3-{[2-(4-fluorophenyl)-2-oxoethyl]amino}bu...)
Affinity DataIC50: 84nMAssay Description:Inhibition of dipeptidyl peptidase 4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

LigandPNGBDBM15464(4-[(3R)-3-{[2-(4-fluorophenyl)-2-oxoethyl]amino}bu...)
Affinity DataIC50: 84nMpH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Eli Lilly

LigandPNGBDBM15469(4-[(3R)-3-{[2-oxo-2-(thiophen-3-yl)ethyl]amino}but...)
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Eli Lilly

LigandPNGBDBM15463(4-[(3R)-3-[(2-oxo-2-phenylethyl)amino]butyl]benzam...)
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Eli Lilly

LigandPNGBDBM15463(4-[(3R)-3-[(2-oxo-2-phenylethyl)amino]butyl]benzam...)
Affinity DataIC50: 280nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Eli Lilly

LigandPNGBDBM15467(4-[(3R)-3-{[2-(4-chlorophenyl)-2-oxoethyl]amino}bu...)
Affinity DataIC50: 820nMpH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Eli Lilly

LigandPNGBDBM15466(4-[(3R)-3-{[2-(2-fluorophenyl)-2-oxoethyl]amino}bu...)
Affinity DataIC50: 3.80E+3nMpH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Eli Lilly

LigandPNGBDBM15468(4-(3-{[2-(4-methylphenyl)-2-oxoethyl]amino}butyl)b...)
Affinity DataIC50: 2.10E+4nMpH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed