Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50368167,50051435,50051436,50280298,50280300,50316222,50368168,50105900   

TargetAdenosylhomocysteinase(Homo sapiens (Human))
Brigham Young University

Curated by ChEMBL
LigandPNGBDBM50051435(5'-Dehydroadenosine | 5'-deoxy-5'-oxoadenosine | 9...)
Affinity DataKi:  39nMAssay Description:concentration dependent inhibition of S-Adenosyl-homocysteine hydrolase was determined by Kitz and Wilson methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50051436((2R,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy...)
Affinity DataKi:  39nMAssay Description:Inhibitory activity against recombinant rat liver S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Brigham Young University

Curated by ChEMBL
LigandPNGBDBM50051436((2R,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy...)
Affinity DataKi:  39nMAssay Description:Binding affinity of the compound towards purified recombinant human placental S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Brigham Young University

Curated by ChEMBL
LigandPNGBDBM50051435(5'-Dehydroadenosine | 5'-deoxy-5'-oxoadenosine | 9...)
Affinity DataKi:  39nMAssay Description:Inhibition of S-adenosyl-L-homocysteine hydrolase, inactivation rate constant.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Brigham Young University

Curated by ChEMBL
LigandPNGBDBM50051435(5'-Dehydroadenosine | 5'-deoxy-5'-oxoadenosine | 9...)
Affinity DataKi:  43nMAssay Description:Binding affinity of the compound towards purified recombinant human placental S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50051435(5'-Dehydroadenosine | 5'-deoxy-5'-oxoadenosine | 9...)
Affinity DataKi:  43nMAssay Description:Inhibitory activity against recombinant rat liver S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Brigham Young University

Curated by ChEMBL
LigandPNGBDBM50051436((2R,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy...)
Affinity DataKi:  43nMAssay Description:concentration dependent inhibition of S-Adenosyl-homocysteine hydrolase was determined by Kitz and Wilson methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50280300((1R,2S,3R)-3-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)
Affinity DataKi:  87nMAssay Description:Compound was tested for its inhibitory activity against recombinant rat liver S-adenosylhomocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosylhomocysteinase(Rattus norvegicus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50280298((1R,2S,3R)-3-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)
Affinity DataKi:  112nMAssay Description:Compound was tested for its inhibitory activity against recombinant rat liver S-adenosylhomocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosylhomocysteinase(Rattus norvegicus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50105900(CHEMBL11390)
Affinity DataKi:  1.00E+3nMAssay Description:Reversible inhibition of rat liver S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50280298((1R,2S,3R)-3-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)
Affinity DataKi:  1.10E+3nMAssay Description:Tested for binding affinity of compound against S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosylhomocysteinase(Rattus norvegicus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50368167(CHEMBL3349334 | CHEMBL611905)
Affinity DataKi:  1.60E+3nMAssay Description:Activity determined in rat liver S-adenosyl-L-homocysteine hydrolase and expressed as Kinactivator values; NA= not applicableMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50280300((1R,2S,3R)-3-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)
Affinity DataKi:  6.90E+3nMAssay Description:Tested for binding affinity of compound against S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosylhomocysteinase(Rattus norvegicus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50368168(CHEMBL609353)
Affinity DataKi:  9.70E+3nMAssay Description:Activity determined in rat liver S-adenosyl-L-homocysteine hydrolase and expressed as Kinactivator values.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50368168(CHEMBL609353)
Affinity DataKi:  9.70E+3nMAssay Description:Competitive inhibitory activity against rat liver S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Mus musculus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50368168(CHEMBL609353)
Affinity DataKi:  1.00E+4nMAssay Description:Activity determined in mouse liver S-adenosyl-L-homocysteine hydrolase and expressed as KI values.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50316222(CHEMBL1095280 | D-ERITADENINE | eritadenine)
Affinity DataIC50:  30nMAssay Description:Inhibition of S-adenosyl-L-homocysteine hydrolase in intact rat hepatocytesMore data for this Ligand-Target Pair