Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50201428,50201434,50201435,50201437,50395738,50395739,50395741,50201428,50201434,50201435,50201437,50395738,50395739,50395741   

TargetCarboxypeptidase B(Pig)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201435(2-(mercaptomethyl)-3-(piperidin-4-yl)propanoic aci...)
Affinity DataIC50: 29nMAssay Description:Inhibition of porcine pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50395741(CHEMBL2164453)
Affinity DataIC50: 34nMAssay Description:Inhibition of human activated TAFI using Hip-Arg as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarboxypeptidase B(Pig)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50395741(CHEMBL2164453)
Affinity DataIC50: 36nMAssay Description:Inhibition of pig pancreatic carboxypeptidase B using Hip-Arg as substrate incubated for 10 mins prior to substrate addition measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarboxypeptidase B2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50201428(3-mercapto-2-(piperidin-4-yl)propanoic acid | CHEM...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human activated thrombin activatable fibrinolysis inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase N catalytic chain(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201428(3-mercapto-2-(piperidin-4-yl)propanoic acid | CHEM...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human carboxypeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase N catalytic chain(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201435(2-(mercaptomethyl)-3-(piperidin-4-yl)propanoic aci...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human carboxypeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50201437(2-(mercaptomethyl)-3-(piperidin-3-yl)propanoic aci...)
Affinity DataIC50: 129nMAssay Description:Inhibition of human activated thrombin activatable fibrinolysis inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50201435(2-(mercaptomethyl)-3-(piperidin-4-yl)propanoic aci...)
Affinity DataIC50: 139nMAssay Description:Inhibition of human activated thrombin activatable fibrinolysis inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Pig)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201428(3-mercapto-2-(piperidin-4-yl)propanoic acid | CHEM...)
Affinity DataIC50: 195nMAssay Description:Inhibition of porcine pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase N catalytic chain(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201437(2-(mercaptomethyl)-3-(piperidin-3-yl)propanoic aci...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human carboxypeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase N catalytic chain(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201437(2-(mercaptomethyl)-3-(piperidin-3-yl)propanoic aci...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human carboxypeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50201434(3-mercapto-2-(piperidin-3-yl)propanoic acid | CHEM...)
Affinity DataIC50: 445nMAssay Description:Inhibition of human activated thrombin activatable fibrinolysis inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Pig)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50395738(CHEMBL2164456)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of pig pancreatic carboxypeptidase B using Hip-Arg as substrate incubated for 10 mins prior to substrate addition measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarboxypeptidase N catalytic chain(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201434(3-mercapto-2-(piperidin-3-yl)propanoic acid | CHEM...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human carboxypeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase N catalytic chain(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201434(3-mercapto-2-(piperidin-3-yl)propanoic acid | CHEM...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human carboxypeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Pig)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201437(2-(mercaptomethyl)-3-(piperidin-3-yl)propanoic aci...)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of porcine pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Pig)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201437(2-(mercaptomethyl)-3-(piperidin-3-yl)propanoic aci...)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of porcine pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50395738(CHEMBL2164456)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human activated TAFI using Hip-Arg as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarboxypeptidase B(Pig)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201434(3-mercapto-2-(piperidin-3-yl)propanoic acid | CHEM...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of porcine pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Pig)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50201434(3-mercapto-2-(piperidin-3-yl)propanoic acid | CHEM...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of porcine pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50395739(CHEMBL2164455)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of human activated TAFI using Hip-Arg as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarboxypeptidase B(Pig)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50395739(CHEMBL2164455)
Affinity DataIC50: 2.60E+5nMAssay Description:Inhibition of pig pancreatic carboxypeptidase B using Hip-Arg as substrate incubated for 10 mins prior to substrate addition measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed