Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 23 hits for monomerid = 50351252,50351509,50351510,50351511,50351512,50351252,50351509,50351510,50351511,50351512
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli JLD271 harboring LasR expression plasmid pJN105L and lasI-lacZ transcri...More data for this Ligand-Target Pair
TargetQuorum-sensing transcriptional repressor QscR(Pseudomonas aeruginosa)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Agonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli assessed as production of beta-galactosidaseMore data for this Ligand-Target Pair
3D Structure (crystal)TargetQuorum-sensing transcriptional repressor QscR(Pseudomonas aeruginosa)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Agonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli assessed as production of beta-galactosidaseMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...More data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 10nMAssay Description:Agonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in absence of natural autoinducerMore data for this Ligand-Target Pair
TargetQuorum-sensing transcriptional repressor QscR(Pseudomonas aeruginosa)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Agonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli assessed as production of beta-galactosidaseMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...More data for this Ligand-Target Pair
TargetQuorum-sensing transcriptional repressor QscR(Pseudomonas aeruginosa)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Agonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli JLD271 harboring QscR expression plasmid pJN105Q and pPA1897-lacZ trans...More data for this Ligand-Target Pair
TargetQuorum-sensing transcriptional repressor QscR(Pseudomonas aeruginosa)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli assessed as production of beta-galactosidaseMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 31nMAssay Description:Agonist activity at Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 33nMAssay Description:Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...More data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Agonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in absence of natural autoinducerMore data for this Ligand-Target Pair
TargetQuorum-sensing transcriptional repressor QscR(Pseudomonas aeruginosa)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 78nMAssay Description:Agonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli assessed as production of beta-galactosidaseMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in presence of 7.5 nM natural auto-inducer 3-oxo-C12-HSLMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 139nMAssay Description:Activation of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...More data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in presence of 7.5 nM natural auto-inducer 3-oxo-C12-HSLMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LuxR(Vibrio fischeri)
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSLMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Agrobacterium tumefaciens)
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSLMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
TargetAccessory gene regulator protein A(Staphylococcus aureus)
University of Nottingham
Curated by ChEMBL
University of Nottingham
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Staphylococcus aureus RN6390B Agr-mediated RNA3 promoter activation measured up to 6 hrs by Northern blot analysisMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: >2.00E+5nMAssay Description:Activation of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
