Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 81357,81358,81360,81361,50318653,81357,81358,81360,81361,50318653   

TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM81357(US8785499, 3_05 | NadD inhibitor 3_05)
Affinity DataIC50: 9.00E+3nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM81358(US8785499, 3_15 | NadD inhibitor 3_15)
Affinity DataIC50: 1.20E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM50318653(NadD inhibitor 3_02 | CHEMBL1084955 | US8785499, 3...)
Affinity DataKi:  1.80E+4nM IC50: 3.60E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM50318653(NadD inhibitor 3_02 | CHEMBL1084955 | US8785499, 3...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of Bacillus anthracis nicotinate-nucleotide adenosyltransferase preincubated for 5 mins before addition of NaMN substrate by malachite gre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM81357(US8785499, 3_05 | NadD inhibitor 3_05)
Affinity DataIC50: 2.00E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM81357(US8785499, 3_05 | NadD inhibitor 3_05)
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
US Patent

TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM50318653(NadD inhibitor 3_02 | CHEMBL1084955 | US8785499, 3...)
Affinity DataKi:  2.10E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM50318653(NadD inhibitor 3_02 | CHEMBL1084955 | US8785499, 3...)
Affinity DataKi:  2.50E+4nM IC50: 6.50E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM50318653(NadD inhibitor 3_02 | CHEMBL1084955 | US8785499, 3...)
Affinity DataKi:  3.20E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM50318653(NadD inhibitor 3_02 | CHEMBL1084955 | US8785499, 3...)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of Bacillus anthracis nicotinate-nucleotide adenosyltransferase preincubated for 5 mins before addition of ATP substrate by malachite gree...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM81358(US8785499, 3_15 | NadD inhibitor 3_15)
Affinity DataIC50: 5.10E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM81358(US8785499, 3_15 | NadD inhibitor 3_15)
Affinity DataIC50: 5.10E+4nMpH: 7.5 T: 2°CAssay Description:A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
US Patent

TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM81361(US8785499, 3_23 | NadD inhibitor 3_23)
Affinity DataIC50: 6.30E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM50318653(NadD inhibitor 3_02 | CHEMBL1084955 | US8785499, 3...)
Affinity DataIC50: 6.50E+4nMpH: 7.5 T: 2°CAssay Description:A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
US Patent

TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM81360(US8785499, 3_17 | NadD inhibitor 3_17)
Affinity DataIC50: 1.70E+5nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM81360(US8785499, 3_17 | NadD inhibitor 3_17)
Affinity DataIC50: 1.70E+5nMpH: 7.5 T: 2°CAssay Description:A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
US Patent

TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM81361(US8785499, 3_23 | NadD inhibitor 3_23)
Affinity DataIC50: 2.00E+5nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM81361(US8785499, 3_23 | NadD inhibitor 3_23)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
US Patent

TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM81360(US8785499, 3_17 | NadD inhibitor 3_17)
Affinity DataIC50: 2.00E+5nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed