Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics

Curated by ChEMBL

LigandBDBM50258255(CHEMBL4062424)Copy SMILESCopy InChI

Affinity DataEC50:  192nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
Sage Therapeutics

Curated by ChEMBL

LigandBDBM50258255(CHEMBL4062424)Copy SMILESCopy InChI

Affinity DataEC50:  1.64E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI