Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
NACHT, LRR and PYD domains-containing protein 3
(Mus musculus)
Guangzhou Medical University
Curated by
ChEMBL
Ligand
BDBM50455476
(CHEBI:6922 | Micheliolide)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.30E+3nM
Assay Description:
Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta release
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
MCE
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NACHT, LRR and PYD domains-containing protein 3
(Homo sapiens (Human))
Guangzhou Medical University
Curated by
ChEMBL
Ligand
BDBM50455476
(CHEBI:6922 | Micheliolide)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.90E+3nM
Assay Description:
Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta release
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
MCE
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Pyruvate kinase PKM
(Homo sapiens (Human))
Nankai University
Curated by
ChEMBL
Ligand
BDBM50455476
(CHEBI:6922 | Micheliolide)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6nM
Assay Description:
Activation of recombinant human PKM2 expressed in Escherichia coli BL21 at 4 uM incubated for 50 mins measured over 40 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI