Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  140nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  1.00E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  2.40E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  2.80E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  3.10E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM579492(US11484525, Compound BD-127-DS | US11484525, Compo...)
Affinity DataKi:  1.10E+4nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Catania

Curated by ChEMBL
LigandPNGBDBM50528976(CHEMBL4474914)
Affinity DataEC50:  4.60nMAssay Description:Inhibition of mu opioid receptor (unknown origin) assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed