Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetSerine/threonine-protein kinase D1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50337696((R)-N-(1-cyanoethyl)-3-(5-(4-(4-methylpiperazin-1-...)Copy SMILESCopy InChI

Affinity DataIC50:  60nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPkd1(Rat)
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50337696((R)-N-(1-cyanoethyl)-3-(5-(4-(4-methylpiperazin-1-...)Copy SMILESCopy InChI

Affinity DataEC50:  570nMAssay Description:Inhibition of PKD1 in rat neonatal ventricular myocytes expressing GFP-HDAC5 assessed as inhibition of phosphorylation-dependent HDAC5 nuclear exportMore data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI