Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Homo sapiens (Human))
Yeda Research and Development

US Patent
LigandPNGBDBM444994(US10668094, Compound DTMS-(silyl))
Affinity DataKi:  11.1nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-2(Homo sapiens (Human))
Yeda Research and Development

US Patent
LigandPNGBDBM444994(US10668094, Compound DTMS-(silyl))
Affinity DataKi:  14.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research and Development

US Patent
LigandPNGBDBM444994(US10668094, Compound DTMS-(silyl))
Affinity DataKi:  24.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Homo sapiens (Human))
Yeda Research and Development

US Patent
LigandPNGBDBM444994(US10668094, Compound DTMS-(silyl))
Affinity DataKi:  72.6nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent