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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
5'-nucleotidase
(Homo sapiens (Human))
Arcus Biosciences
Curated by
ChEMBL
Ligand
BDBM50546288
(CHEMBL4743437)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.00270nM
Assay Description:
Inhibition of CD73 in human CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5'-nucleotidase
(Homo sapiens (Human))
Arcus Biosciences
Curated by
ChEMBL
Ligand
BDBM50546288
(CHEMBL4743437)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.00850nM
Assay Description:
Inhibition of CD73 in human PBMC using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2.5 hrs by PiColor...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5'-nucleotidase
(Homo sapiens (Human))
Arcus Biosciences
Curated by
ChEMBL
Ligand
BDBM50546288
(CHEMBL4743437)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.0450nM
Assay Description:
Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5'-nucleotidase
(Homo sapiens (Human))
Arcus Biosciences
Curated by
ChEMBL
Ligand
BDBM50546288
(CHEMBL4743437)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.0530nM
Assay Description:
Inhibition of soluble human CD73
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5'-nucleotidase
(Mus musculus)
Arcus Biosciences
Curated by
ChEMBL
Ligand
BDBM50546288
(CHEMBL4743437)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.160nM
Assay Description:
Inhibition of CD73 in mouse CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ectonucleoside triphosphate diphosphohydrolase 8
(Homo sapiens (Human))
Arcus Biosciences
Curated by
ChEMBL
Ligand
BDBM50546288
(CHEMBL4743437)
Copy SMILES
Copy InChI
Affinity Data
IC50: >10nM
Assay Description:
Inhibition of NTPDase 8 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ectonucleoside triphosphate diphosphohydrolase 1
(Homo sapiens (Human))
Arcus Biosciences
Curated by
ChEMBL
Ligand
BDBM50546288
(CHEMBL4743437)
Copy SMILES
Copy InChI
Affinity Data
IC50: >10nM
Assay Description:
Inhibition of CD39 (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ectonucleoside triphosphate diphosphohydrolase 2
(Homo sapiens (Human))
Arcus Biosciences
Curated by
ChEMBL
Ligand
BDBM50546288
(CHEMBL4743437)
Copy SMILES
Copy InChI
Affinity Data
IC50: >10nM
Assay Description:
Inhibition of NTPDase 2 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ectonucleoside triphosphate diphosphohydrolase 3
(Homo sapiens (Human))
Arcus Biosciences
Curated by
ChEMBL
Ligand
BDBM50546288
(CHEMBL4743437)
Copy SMILES
Copy InChI
Affinity Data
IC50: >10nM
Assay Description:
Inhibition of NTPDase 3 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI