Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 18 hits in this display   

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50:  250nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50:  250nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50:  250nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50:  9.32E+4nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50:  9.32E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50:  9.32E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetBone morphogenetic protein receptor type-1A(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetBone morphogenetic protein receptor type-1B(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetSerine/threonine-protein kinase receptor R3(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetActivin receptor type-1(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetBone morphogenetic protein receptor type-1A(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetActivin receptor type-1(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetSerine/threonine-protein kinase receptor R3(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetBone morphogenetic protein receptor type-1B(Mouse)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetBone morphogenetic protein receptor type-1A(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetBone morphogenetic protein 10(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetSerine/threonine-protein kinase receptor R3(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI

TargetActivin receptor type-1(Human)
Medivation Technologies

US Patent

LigandBDBM280336(4-[[5-bromo-2-(5-chloro-2-fluoro-phenyl)-4-pyridyl...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI