Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 25 hits in this display   

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  20.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  20.4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  20.4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  20.4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  32.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  32.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  32.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  32.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein 10(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1B(Mouse)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent