Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 24 hits in this display   

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  42.2nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  42.2nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  42.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  42.2nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  114nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  114nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  114nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  114nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  7.30E+3nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  7.30E+3nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  7.30E+3nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  7.30E+3nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein 10(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1B(Mouse)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent