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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
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Target
Glucose-6-phosphate 1-dehydrogenase
(Human)
University of Manchester
Curated by
ChEMBL
Ligand
BDBM50191342
(3alpha-hydroxy-5alpha-pregnan-20-one | CHEMBL20753...)
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Affinity Data
IC50: 6.60E+4nM
Assay Description:
Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...
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Target
Gamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta
(Human)
Sage Therapeutics
Curated by
ChEMBL
Ligand
BDBM50191342
(3alpha-hydroxy-5alpha-pregnan-20-one | CHEMBL20753...)
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Affinity Data
EC50: 76nM
Assay Description:
Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...
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3D Structure (crystal)
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Target
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2
(Human)
Sage Therapeutics
Curated by
ChEMBL
Ligand
BDBM50191342
(3alpha-hydroxy-5alpha-pregnan-20-one | CHEMBL20753...)
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Affinity Data
EC50: 237nM
Assay Description:
Inhibition of human ERG by patch clamp assay
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Target
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2
(Human)
Sage Therapeutics
Curated by
ChEMBL
Ligand
BDBM50191342
(3alpha-hydroxy-5alpha-pregnan-20-one | CHEMBL20753...)
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Affinity Data
EC50: 160nM
Assay Description:
Potentiation of GABA-activated currents in Xenopus oocytes expressing cloned human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor
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Target Info
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antibodypedia
antibodypedia
antibodypedia
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Ligand Info
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ChEBI
CHEMBL
KEGG
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PC sid
PDB
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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