Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50349770(CHEMBL1809191)Copy SMILESCopy InChI

Affinity DataIC50:  78nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50349770(CHEMBL1809191)Copy SMILESCopy InChI

Affinity DataIC50:  270nMAssay Description:Inhibition of IGF1-induced autophosphorylation of human recombinant IGF1R expressed in mouse fibroblasts by high throughput assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI