Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL

LigandBDBM50593015(CHEMBL5182795)Copy SMILESCopy InChI

Affinity DataIC50:  13nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University

Curated by ChEMBL

LigandBDBM50593015(CHEMBL5182795)Copy SMILESCopy InChI

Affinity DataIC50:  871nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI