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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center For Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)
Affinity DataKi:  7.84E+3nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center For Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)
Affinity DataKi:  1.38E+4nMAssay Description:Inhibition constant against DNA polymerase alpha competitively on DNA templateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50097532(CHEMBL354794 | [17-(1,5-Dimethyl-hexyl)-10,13-dime...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity tested against cell division cycle 25A (assay using fluorescein diphosphate (FDP) as substrate)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center For Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory concentration against human DNA polymerase alpha incubated with 0.05 unitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Frontier Research Center For Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory concentration against rat DNA polymerase beta incubated with 0.05 unitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed