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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50038526(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclopentyl...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory activity against ACAT was determined in rabbit intestinal microsome from cholesterol-fed animalsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50038526(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclopentyl...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibition of rat intestinal acyl coenzyme A:cholesterol acyltransferase using [1-14C]oleolyl-CoAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50038526(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclopentyl...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50038526(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclopentyl...)
Affinity DataIC50:  17nMAssay Description:Tested for in vitro inhibition against Acyl coenzyme A:cholesterol acyltransferase of intestinal microsomes in cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed