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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50040468(2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethy...)
Affinity DataIC50:  4.00E+3nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50040468(2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethy...)
Affinity DataIC50:  5.20E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]-oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50040468(2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethy...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of Acyl-CoA: Cholesterol Acyltransferase (ACAT) in liver microsomes of cholesterol fed ratsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50040468(2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethy...)
Affinity DataIC50:  5.30E+3nMAssay Description:In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase 1 in microsomes of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50040468(2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethy...)
Affinity DataIC50:  5.30E+3nMAssay Description:Compound was evaluated for the Acyl coenzyme A:cholesterol acyltransferase inhibition using microsomes isolated from the livers of cholesterol fed ra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed