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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
)
Found
2
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Target
WD repeat-containing protein 48
(Human)
National Center For Advancing Translational Sciences
Curated by
ChEMBL
Ligand
BDBM352014
(US9802904, 75)
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Affinity Data
IC50: 90nM
Assay Description:
Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay
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UniProtKB/SwissProt
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Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48
(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Ligand
BDBM352014
(US9802904, 75)
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Affinity Data
IC50: 2.20E+3nM
Assay Description:
This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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