Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Homo sapiens (Human))
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent

LigandBDBM352015(US9802904, 76)Copy SMILESCopy InChI

Affinity DataIC50:  120nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetWD repeat-containing protein 48(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

LigandBDBM352015(US9802904, 76)Copy SMILESCopy InChI

Affinity DataIC50:  140nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI